Could less radiation be just as good for bone cancer pain?

NCT ID NCT06884332

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether reducing the amount of spine radiated for painful bone metastases can still effectively relieve pain while possibly causing fewer side effects. About 600 people with spinal bone metastases will be randomly assigned to receive either standard radiation (covering the tumor plus one vertebra above and below) or a smaller radiation field (covering only the tumor and the affected vertebra). The main goal is to compare pain relief at 30 days after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

radiation therapy

What this could lead to

If successful, this could show that smaller radiation fields are just as good for pain relief, with fewer side effects, improving quality of life for people with bone metastases.

What could go wrong

This is a mid-sized trial, but results may not apply to all patients. There is a risk that reducing the radiation area might not control pain as well as the standard approach.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cancer Pain metastatic carcinoma in the bone

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Henri Becquerel Rouen

    RECRUITING

    Rouen, Rouen, 76038, France

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire de Brest

    RECRUITING

    Brest, Brest, 29609, France

    Contact Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de Cancérologie de Lorraine

    RECRUITING

    Vandœuvre-lès-Nancy, 54511, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut de cancérologie de l'Ouest (ICO)

    RECRUITING

    Saint-Herblain, Saint-Herblain, 44805, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact