Astrazeneca

This study tests a combination of two targeted drugs (acalabrutinib and venetoclax) for people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) whose cancer has returned after previous treatment. The goal is to see if this short-term therapy can control…

This study tests a new drug called surovatamig in people with a type of leukemia (CLL/SLL) that has a genetic marker (unmutated IGHV) making it harder to treat. After finishing their first round of treatment, participants will either receive surovatamig or be watched without extr…

This study is a safety check required by Korean health authorities. It will follow 600 adults with COPD who are starting Breztri to see how well the drug works and what side effects occur in everyday use. The goal is to confirm the drug's safety in a real-world setting, not to fi…

This study will follow about 80 Polish patients with atypical hemolytic uremic syndrome (aHUS) who are receiving ravulizumab as part of routine care. Researchers will collect data from medical records and regular check-ups to see how well the treatment controls the disease. The g…

This early-stage study tests an experimental drug called AZD8359 in 42 adults with metastatic prostate cancer that has worsened despite prior treatments. The drug is designed to help the immune system attack cancer cells. The study aims to find the safest and most effective dose …

This study looks at the long-term safety of a drug called tozorakimab in people with chronic obstructive pulmonary disease (COPD) who have had flare-ups in the past. About 82 adults who already completed a related study will receive the drug and be monitored for side effects. The…

This study monitors the safety and effectiveness of Tezepelumab (Tezspire) in 210 people with severe asthma in South Korea. Researchers will track side effects and asthma control over 24 weeks during routine treatment. The goal is to ensure the drug works well and is safe in ever…

This study is for people with a type of lung cancer (EGFR-mutant NSCLC) that has spread to other parts of the body after they finished a targeted therapy called osimertinib. The goal is to see if giving osimertinib together with chemotherapy can help control the cancer for longer…

This study tests two experimental drugs, camizestrant and atirmociclib, taken together by people with a certain type of advanced breast cancer (ER-positive, HER2-negative) that has worsened after previous treatment. The main goal is to check the safety of the combination and see …

This study offers continued treatment with benralizumab (Fasenra) to about 230 adults with asthma, eosinophilic granulomatosis with polyangiitis (EGPA), or hypereosinophilic syndrome (HES) who completed a previous benralizumab study and are still benefiting. The main goal is to m…

This study is testing a new drug called AZD9750 for men with metastatic prostate cancer that has spread. Researchers want to see if the drug is safe, how the body processes it, and if it shows early signs of fighting the cancer. The trial will test AZD9750 alone and combined with…

This study aims to see if training doctors on a standardized process helps them identify ATTR amyloidosis earlier in people at high risk. About 4,000 adults aged 60 and older with heart failure will be enrolled across 50 sites in China. Doctors will receive special training on di…

This study aims to see if a portable breathing test (oscillometry) can accurately diagnose asthma compared to standard tests. Researchers will enroll 500 adults in China who have asthma symptoms like wheezing or coughing. If successful, this could make asthma diagnosis quicker an…

This study tests a drug called tezepelumab in 230 Chinese adults with chronic sinusitis and nasal polyps. The goal is to see if the drug can shrink polyps and reduce congestion over 24 weeks. Participants receive the drug as an injection, and doctors measure changes using nasal e…

This study tests if a dexamethasone mouthwash can prevent or reduce painful mouth sores caused by the cancer drug datopotamab deruxtecan. About 100 adults with advanced breast or lung cancer will use the mouthwash and be monitored for 12 weeks. The goal is to improve quality of l…

This study interviews about 85 lung cancer patients and 15 doctors in China to find out what makes it easier or harder for patients to keep taking the targeted therapy osimertinib after surgery. The goal is to identify barriers like side effects, cost, or communication issues, an…

This study will observe about 477 Brazilian smokers aged 50-80 to see how well lung cancer screening works in a region where other lung diseases are common. The goal is to find out how often screening gives false alarms, which can lead to extra tests and worry. Researchers hope t…

This study aims to understand genetic changes in metastatic prostate cancer and how they affect patient outcomes. It will involve 100 adults in Brazil who are receiving standard palliative therapy. Researchers will analyze tumor and blood samples to identify key mutations, but no…

This study will look back at medical records of 3000 people in China with early-stage non-small cell lung cancer (stages I to III). The goal is to understand which treatments doctors use, how often biomarker testing is done, and what happens to patients over time. No new treatmen…

This study will track the use of Saphnelo (anifrolumab) in up to 26 million women with lupus who are of childbearing age. The goal is to see how often the drug is prescribed and understand its safety in pregnancy. No new treatments are given—researchers will simply observe real-w…