Lupus drug saphnelo under Real-World watch in women

NCT ID NCT07431775

Not yet recruiting Knowledge-focused Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will look at how the lupus medication Saphnelo (anifrolumab) is being used in women aged 15 to 50 who could become pregnant. Researchers will track how many women use the drug each year and describe their health characteristics. The goal is to gather real-world information to better understand safety in pregnancy, as required by health authorities.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Anifrolumab (Saphnelo)
What this could lead to
If successful, this study will provide real-world data on how Saphnelo is used in women who could become pregnant, helping to guide safer use and inform pregnancy-related safety.
What could go wrong
This is an observational study, not a treatment trial, so it won't test if Saphnelo works or is safe. Results depend on the quality of existing medical records and may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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