VALVULAR HEART DISEASE

This study tests a home-based exercise program delivered through a mobile app for people who had heart valve procedures. Many patients don't attend traditional center-based rehab, so this offers a convenient alternative. About 240 participants will be randomly assigned to usual c…

This study tests whether a special method of expanding a replacement heart valve during TAVI can reduce harmful thickening of the valve leaflets. About 620 people with severe aortic stenosis who do not have atrial fibrillation will be randomly assigned to either the new expansion…

This study tests a hospital-wide treatment plan for people with heart failure and a leaky mitral valve (secondary mitral regurgitation). The goal is to see if the plan helps doctors identify who will benefit most from a minimally invasive valve repair procedure called MitraClip. …

This study is testing whether a special wristwatch that shines light through the skin (called PPG) can estimate how well the heart pumps blood and detect heart valve or muscle diseases. About 500 adults getting a heart ultrasound will wear the watch to see if its signals match st…

This study tests whether artificial intelligence (AI) can help heart doctors read echocardiograms (heart ultrasounds) more quickly and consistently. Researchers will give AI analysis to cardiologists in real time as they review scans for valve disease. The goal is to see if AI re…

This study is following 4,000 adults with heart valve disease to discover new risk factors and understand how certain natural chemicals (metabolites) in the body influence the disease. Researchers will track participants over time and test tissue samples. The goal is to learn mor…

This study aims to improve how we detect and understand heart disease using advanced MRI scans. Researchers will compare new MRI techniques with standard tests in 1,000 adults, both healthy volunteers and those with various heart conditions. The goal is to find better ways to see…

This study is a large registry that will follow 2500 people who receive Abbott heart devices (like those for hole-in-heart repairs or valve disease) during routine care. The goal is to confirm the devices are safe and work well in everyday hospital practice. Participants just rec…

This study looks at 82 adults with severe aortic stenosis who need open-heart valve replacement. It compares valve size measurements from a pre-surgery CT scan with those taken during surgery. The goal is to see which method is more accurate for picking the right valve size.