New TAVI technique aims to stop silent valve clots

NCT ID NCT07042529

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special method to expand a new heart valve during TAVI can reduce harmful thickening of the valve leaflets. About 620 people with severe aortic stenosis who do not have atrial fibrillation will be randomly assigned to either the optimized expansion method or standard care. The main goal is to see if the new approach leads to less leaflet thickening on a CT scan three months after the procedure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis heart valve disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aalborg University Hospital

    NOT_YET_RECRUITING

    Aalborg, 9000, Denmark

    Contact Email: •••••@•••••

  • CHU Charleroi

    NOT_YET_RECRUITING

    Charleroi, 6000, Belgium

    Contact Email: •••••@•••••

  • Odense University Hospital

    NOT_YET_RECRUITING

    Odense C, 5000, Denmark

    Contact Email: •••••@•••••

  • Oslo universitetssygehus

    NOT_YET_RECRUITING

    Oslo, 0450, Norway

    Contact Email: •••••@•••••

  • Rigshospitalet

    RECRUITING

    Copenhagen, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sahlgrenska University Hospital

    NOT_YET_RECRUITING

    Gothenburg, 413 45, Sweden

    Contact Email: •••••@•••••

  • Skejby Hospital

    NOT_YET_RECRUITING

    Aa, 8200, Denmark

    Contact Email: •••••@•••••

  • St. Antonius Hospital

    NOT_YET_RECRUITING

    Nieuwegein, 3435, Netherlands

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Turku University Hospital

    NOT_YET_RECRUITING

    Turku, 20520, Finland

    Contact Email: •••••@•••••

  • UZ Leuven

    NOT_YET_RECRUITING

    Leuven, 3000, Belgium

    Contact Email: •••••@•••••