New TAVI technique aims to stop silent valve clots
NCT ID NCT07042529
First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time
Summary
This study tests whether a special method to expand a new heart valve during TAVI can reduce harmful thickening of the valve leaflets. About 620 people with severe aortic stenosis who do not have atrial fibrillation will be randomly assigned to either the optimized expansion method or standard care. The main goal is to see if the new approach leads to less leaflet thickening on a CT scan three months after the procedure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for AORTIC STENOSIS DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AZ Delta
RECRUITINGRoeselare, Belgium
-
AZORG ziekenhuis
RECRUITINGAalst, Belgium
-
Aalborg University Hospital
RECRUITINGAalborg, 9000, Denmark
-
CHU Charleroi
RECRUITINGCharleroi, 6000, Belgium
-
Haukeland hospital
RECRUITINGHaukeland, Norway
-
Leiden University Medical Center
RECRUITINGLeiden, Netherlands
-
Odense University Hospital
NOT_YET_RECRUITINGOdense C, 5000, Denmark
-
Oslo universitetssygehus
RECRUITINGOslo, 0450, Norway
-
Rigshospitalet
RECRUITINGCopenhagen, Denmark
-
Sahlgrenska University Hospital
RECRUITINGGothenburg, 413 45, Sweden
-
Skejby Hospital
NOT_YET_RECRUITINGAa, 8200, Denmark
-
Skånes universitetssjukhus
RECRUITINGSkåne, Sweden
-
St. Antonius Hospital
RECRUITINGNieuwegein, 3435, Netherlands
-
Turku University Hospital
RECRUITINGTurku, 20520, Finland
-
UMC Amsterdam
RECRUITINGAmsterdam, Netherlands
-
UZ Leuven
RECRUITINGLeuven, 3000, Belgium
-
University Medical Center Groningen
RECRUITINGGroningen, Netherlands
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- A painless, contact-free vibration sensor may detect hidden heart and lung problems
- Prepping the body before heart surgery: could exercise shorten hospital stays?
- New flowchart could reduce ICU time and pacemakers after TAVR
- Simple exercise test may predict TAVI success
- Nutrition check before heart surgery may flag lung risks in seniors
- New study tracks heart damage before and after valve procedure