SUBSTANCE USE
Clinical trials for SUBSTANCE USE explained in plain language.
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App and video counseling aim to help young adults control HIV
Disease control OngoingThis study is testing whether a technology-based support program can help young adults (18-29) living with HIV better control their virus. The program combines weekly video chats with a counselor and a smartphone app to help with medication reminders, mental health, and social co…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Can a smartphone app curb teen violence? AI therapy study aims to find out
Disease control OngoingThis study is testing two versions of a remote therapy program delivered via smartphone to help teens and young adults (ages 14-24) who were treated in the emergency room for a violent injury. The goal is to reduce their future involvement in violence, aggression, and related ris…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Can a phone app and a peer coach help young adults with trauma drink less?
Disease control OngoingThis study is testing a new mobile phone program designed to help young adults (ages 18-25) who have experienced trauma and drink heavily. The program teaches coping skills for trauma-related stress and connects participants with a peer coach for support via text message. Researc…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Western Kentucky University • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New study aims to break the cycle of disease and addiction after jail
Disease control OngoingThis study compares two ways to help people recently released from jail or prison get connected to important health services. It focuses on HIV prevention and treatment, hepatitis C care, and medication for opioid addiction. Researchers will test whether personal guides or mobile…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Yale University • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Can video calls help people cut back on drinking?
Disease control OngoingThis study is testing whether a telehealth program delivered by video or phone can help people with alcohol use disorder start treatment and reduce their drinking. Researchers are comparing this remote program to standard care to see which approach works better. The goal is to fi…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: University of Michigan • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Street-Level fight against tobacco: can a Plant-Based pill help where others failed?
Disease control ENROLLING_BY_INVITATIONThis study tests two practical strategies to help homeless or at-risk adults in Ottawa and Toronto quit or reduce smoking and other substance use. It compares a plant-based medication called Cytisine with standard nicotine replacement therapy (like sprays or gum), both combined w…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Ottawa Hospital Research Institute • Aim: Disease control
Last updated Mar 16, 2026 15:24 UTC
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Text message help for young drinkers with trauma
Disease control TerminatedThis study aimed to test an improved mobile app designed to help young adults (ages 18-29) who have experienced trauma and engage in heavy drinking. The app would teach coping skills and connect users with a peer coach for support via text messages. Researchers planned to compare…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Western Kentucky University • Aim: Disease control
Last updated Mar 11, 2026 14:54 UTC
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Can your genes help you avoid addiction? new program aims to find out
Prevention OngoingThis study is testing a new online program designed to prevent substance use problems in young adults aged 18-25. The program creates a personalized risk profile for each participant by combining their genetic information with details about their lifestyle and environment. Resear…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Prevention
Last updated Apr 01, 2026 14:43 UTC
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New approach aims to protect couples from HIV and drug use
Prevention OngoingThis study is testing whether adding special training videos and substance use counseling to standard couples HIV testing helps reduce drug use and HIV transmission risk. It involves 484 male couples where one partner has recently used drugs and engaged in higher-risk sexual beha…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Hunter College of City University of New York • Aim: Prevention
Last updated Mar 30, 2026 14:30 UTC
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Ottawa study seeks to unlock why homeless youth turn to drugs and tobacco
Knowledge-focused ENROLLING_BY_INVITATIONThis research project aims to understand why homeless or at-risk youth in Ottawa use multiple substances like tobacco, cannabis, and other drugs. The study will work directly with about 520 young people and adults, using surveys and interviews to learn about their experiences. Ba…
Matched conditions: SUBSTANCE USE
Sponsor: Ottawa Hospital Research Institute • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists scan brains to unlock secrets of opioid use in pregnancy
Knowledge-focused OngoingThis study aims to understand how opioid use disorder (OUD) and its treatment medication affect the brain during pregnancy. Researchers will use MRI scans to compare brain connections in 40 pregnant women with OUD to those without OUD. The goal is to gather knowledge that could o…
Matched conditions: SUBSTANCE USE
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Can cash bonuses make addiction counseling better?
Knowledge-focused OngoingThis study tests whether paying bonuses to staff at HIV service organizations improves how they deliver a brief counseling method for substance use. It involves 428 staff and clients across the U.S. The main goal is to see if this 'pay-for-performance' strategy leads to more cons…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:19 UTC
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Scientists track young Adults' brains to unlock secrets of risky behavior
Knowledge-focused OngoingThis study aims to understand how the developing brain influences decisions about substance use and other health risks in young adulthood. Researchers are following a group of people they have been studying since adolescence, now aged 23-28, to see how their thinking patterns rel…
Matched conditions: SUBSTANCE USE
Phase: NA • Sponsor: Virginia Polytechnic Institute and State University • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:53 UTC