Can a smartphone app and video therapy help young people with HIV?

NCT ID NCT05877729

Ongoing Disease control Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of weekly video-counseling sessions and a mobile app can help young adults (18-29) living with HIV achieve viral suppression. Participants who are not virally suppressed will be randomly assigned to receive the intervention or standard care. The program aims to address barriers like medication forgetfulness, mental health issues, and substance use. The trial will compare viral suppression rates and mental health outcomes after 16 weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: video-counseling plus mobile health app
What this could lead to: If successful, this could provide an effective, scalable way to help young people with HIV achieve viral suppression and improve mental health and substance use outcomes.
What could go wrong: This is a relatively small, early-stage trial (200 participants) testing a behavioral intervention, not a drug. Results may not generalize to all populations, and the intervention requires active participation, which may limit real-world impact.

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV/AIDS MENTAL HEALTH ISSUE MOBILE HEALTH SUBSTANCE USE YOUNG ADULT

Contacts and locations

Locations

Division of Prevention Science, Center for AIDS Prevention Studies (CAPS)

San Francisco, California, 94143, United States

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