STRESS DISORDERS, POST-TRAUMATIC
Clinical trials for STRESS DISORDERS, POST-TRAUMATIC explained in plain language.
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New combo therapy helps veterans quit smoking and tackle PTSD
Disease control CompletedThis study tested a new treatment for veterans who smoke and have PTSD. It combined a proven PTSD therapy with extra support to help them quit smoking, including counseling and rewards for staying smoke-free. 120 veterans took part to see if this approach helped them stop smoking…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated May 17, 2026 04:14 UTC
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New eScreening tool helps VA spot depression and suicide risk faster in veterans
Diagnosis CompletedThis study looked at whether an electronic self-report screening system (eScreening) helps VA clinics detect depression, PTSD, alcohol problems, and suicide risk more quickly and more often in newly enrolled veterans. Researchers compared screening rates and referral times before…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Diagnosis
Last updated May 15, 2026 11:55 UTC
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New brain zaps could ease PTSD without talk therapy
Symptom relief CompletedThis study tested a new way to treat PTSD in veterans and active-duty service members using a type of brain stimulation called transcranial magnetic stimulation (TMS). Instead of the usual weeks of therapy, participants received daily TMS sessions over just two weeks. The goal wa…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Symptom relief
Last updated May 17, 2026 04:27 UTC
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New program helps veterans with PTSD break free from safety crutches
Symptom relief CompletedThis study tested a 10-week group program called START for 45 veterans with PTSD who had not responded to other treatments. The program aimed to help them reduce their use of safety behaviors (like always carrying a weapon or avoiding certain places) and see if that lowered their…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 17, 2026 04:16 UTC
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Smartwatch app wakes veterans from nightmares, improves sleep
Symptom relief CompletedThis study tested a digital system (iPhone + Apple Watch with a special app) designed to detect and interrupt nightmares in people with PTSD. The goal was to improve sleep quality without fully waking the person. 270 veterans and active-duty service members took part. The study m…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: NightWare • Aim: Symptom relief
Last updated May 17, 2026 04:15 UTC
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Sleep therapy boosts quality of life for veterans with PTSD
Symptom relief CompletedThis study tested a behavioral sleep treatment in 36 veterans who have PTSD, insomnia, and sleep apnea. The goal was to see if improving sleep helps them function better and feel better overall. Participants attended therapy sessions and reported on their quality of life and dail…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: PHASE2 • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated May 17, 2026 04:13 UTC
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Can online writing ease PTSD and heavy drinking in LGBTQ+ communities?
Symptom relief CompletedThis study tested if tailored online writing exercises could help sexual minority women, transgender, and nonbinary people who have experienced trauma and struggle with heavy drinking. 131 participants completed the program. The goal was to see if these writing exercises could re…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: Syracuse University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Could recalling happy memories help heal PTSD?
Symptom relief CompletedThis study tested a new therapy called Processing of Positive Memories Technique (PPMT) for people with PTSD. Unlike standard treatments that focus on trauma, PPMT helps patients recall and describe positive memories. 70 adults with PTSD were randomly assigned to either PPMT or s…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: University of North Texas, Denton, TX • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Veterans' nightmares tracked at home to unlock better treatments
Knowledge-focused CompletedThis study monitored the sleep of 48 Veterans with trauma-related nightmares using special mattress sensors in their own homes. The goal was to learn how nightmares affect sleep and how these patterns change with a cognitive-behavioral treatment. Results will help doctors persona…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 17, 2026 04:31 UTC
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Weekly vs. daily: can a new schedule keep veterans in PTSD therapy?
Knowledge-focused CompletedThis study looked at whether offering PTSD therapy several times a week (massed) helps veterans complete their treatment compared to the usual once-a-week schedule. Thirty veterans with PTSD took part, and researchers measured how many finished therapy, how satisfied they were, a…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 17, 2026 04:30 UTC
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Diary program aims to ease family trauma after Child's ICU stay
Knowledge-focused CompletedThis study tested whether having families keep a hospital diary during their child's stay in the pediatric intensive care unit (PICU) could reduce anxiety, depression, and post-traumatic stress after discharge. Researchers followed 431 families in four Brazilian PICUs, checking t…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: D'Or Institute for Research and Education • Aim: Knowledge-focused
Last updated May 17, 2026 04:30 UTC
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Brain training: can classes build PTSD resilience?
Knowledge-focused CompletedThis study looked at whether a short course teaching cognitive behavioral therapy (CBT) skills could increase a specific brain connectivity pattern linked to resilience against PTSD. It involved 30 public safety personnel (like police or firefighters) who were already part of a l…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: University of Manitoba • Aim: Knowledge-focused
Last updated May 17, 2026 04:18 UTC
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New 10-Question test could help nurses spot hidden PTSD after car crashes
Knowledge-focused CompletedThis study tested a short 10-question screening tool called DEPITAC to help nurses identify post-traumatic stress disorder (PTSD) in people hospitalized after a road accident. About 274 participants completed the questionnaire within two weeks of their accident. The goal was to s…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 17, 2026 04:17 UTC
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Pandemic's hidden toll: 7 in 10 ICU staff show PTSD symptoms
Knowledge-focused CompletedThis study looked at how working in intensive care during the COVID-19 outbreak affected the mental health of doctors, nurses, and other caregivers. Over 700 healthcare workers answered surveys about post-traumatic stress, anxiety, depression, and burnout. The goal was to underst…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC
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Brain wave test could personalize mental health treatment for veterans
Knowledge-focused CompletedThis study looked at 100 veterans with mental health conditions like schizophrenia, PTSD, anxiety, or mood disorders. The goal was to see if a simple brain wave test (called mismatch negativity) could help choose the best thinking skills training for each person. Researchers meas…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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H1N1 survivors' lungs still show damage years after ICU
Knowledge-focused CompletedThis study followed 38 adults who survived severe H1N1 flu that caused lung failure. Researchers compared those who needed a machine to add oxygen to their blood with those who did not. They measured lung function, quality of life, and mental health at least 9 months after leavin…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated May 12, 2026 13:41 UTC
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Teen PTSD brain scans reveal memory and emotion links
Knowledge-focused CompletedThis study looked at how psychological trauma changes the way teenagers' brains handle memory and emotions. Researchers used MRI scans to compare brain activity in 19 teens with PTSD and healthy teens. The goal was to better understand the brain areas involved, not to test a trea…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: University Hospital, Caen • Aim: Knowledge-focused
Last updated May 11, 2026 20:41 UTC
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ICU breathing tubes linked to brain fog: new study reveals lasting effects
Knowledge-focused CompletedThis study followed 125 ICU patients who needed a breathing tube and sedation for at least 48 hours. Researchers checked for memory and thinking problems 4 months after leaving the ICU. They also looked at stress, depression, and other factors. The goal was to understand how comm…
Matched conditions: STRESS DISORDERS, POST-TRAUMATIC
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC