STOMACH NEOPLASMS

This early-stage study is testing a new type of personalized cell therapy for people with advanced solid tumors, including mesothelioma, that have come back or spread after standard treatments. Doctors collect a patient's own immune cells, genetically modify them in a lab to bett…

This early-stage study is testing a new radioactive cancer drug called LY4337713 in adults with advanced solid tumors that have spread. The drug is designed to seek out and deliver radiation directly to cancer cells that have a specific protein marker called FAP. Researchers will…

This study aims to find the best way to treat small, precancerous growths in the stomach. Researchers are comparing two common procedures—one that burns the growth away and one that cuts it out—to see which is safer and just as effective at preventing it from coming back. About 1…

This study aims to find out if a less invasive 'keyhole' surgery (laparoscopic) is as effective as traditional open surgery for treating advanced stomach cancer. It will follow over 1,000 patients to compare their long-term survival, cancer recurrence, and recovery after surgery.…

This study is testing a new combination of two cancer drugs, disitamab vedotin and tucatinib, for people with advanced or spreading breast or stomach cancer. The main goals are to find a safe and effective dose and to see if the combination can shrink tumors. It is for people who…

This study compares two different stomach cancer surgeries to see which one works better for patients with advanced tumors where the stomach meets the esophagus. Patients will be randomly assigned to receive either a partial stomach removal or a complete stomach removal, then fol…

This early-stage trial is testing the safety and dosing of an experimental drug called PF-08046050 in adults with advanced solid tumors that have returned or stopped responding to standard treatments. The drug is designed to attach to cancer cells and deliver a toxic payload dire…

This study is testing whether a combination of targeted cancer drugs can shrink tumors in patients with advanced stomach cancer that cannot be removed by surgery right away. The goal is to see if giving these drugs before and after surgery can better control the cancer. The trial…

This study is for people with advanced stomach cancer that has gotten worse after their first treatment. It will test if a new three-drug combination works better and is safe enough compared to a standard single chemotherapy drug. The goal is to see if the new combination can bet…

This early-stage trial is testing an experimental drug called sigvotatug vedotin for people with advanced solid tumors that have spread or cannot be removed by surgery. The study will first determine safe doses, then test the drug alone and in combination with other cancer medica…

This study is testing whether adding an immunotherapy drug called serplulimab to standard chemotherapy before surgery is more effective for treating locally advanced stomach or gastroesophageal junction cancer. Researchers will compare the new combination to chemotherapy alone in…

This study aims to see if small tissue samples taken during an endoscopy (a tube with a camera) are just as good as larger samples taken during surgery for identifying important features of stomach cancer. Researchers will compare results from both types of samples from 510 patie…

This study aims to collect blood, urine, and tumor samples from up to 1,000 patients with mesothelioma and other related cancers. The purpose is to build a tissue bank for future research to better understand these diseases. Participants will be followed over time to track their …