New combo therapy targets stomach cancer lymph nodes

NCT ID NCT07007182

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests whether adding surgery and radiation to standard chemotherapy can improve outcomes for people with stomach cancer that has spread only to nearby lymph nodes. About 54 participants will receive either standard chemo or a more intensive plan including chemo, surgery, and radiation. The goal is to see if the combined approach helps control the disease longer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SOX regimen (oxaliplatin plus S-1) or CAPEOX regimen (oxaliplatin plus capecitabine), with or without a PD-1 inhibitor

What this could lead to

If successful, this could offer a more effective treatment plan for gastric cancer patients with lymph node spread, potentially improving survival and disease control.

What could go wrong

This is a small, early-phase trial with only 54 participants, so results may not apply to all patients. The added treatments also carry risks like side effects from chemo and radiation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shandong Cancer Hospital and Institute

    RECRUITING

    Jinan, Shandong, 250117, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••