Triple-Drug cocktail aims to extend life in tough stomach cancer

NCT ID NCT07309185

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether adding two drugs (adebrelimab and famitinib) to standard chemotherapy (irinotecan) can help people with advanced stomach or gastroesophageal junction cancer whose first treatment stopped working. About 66 participants will be randomly assigned to receive either the three-drug combo or irinotecan alone. The main goal is to see if the combo delays cancer growth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Adebrelimab, famitinib malate, and irinotecan

What this could lead to

If successful, this combination could offer a new treatment option for advanced gastric cancer patients who have run out of standard options.

What could go wrong

This is a small, early-phase exploratory study with only 66 participants, so results may not apply broadly. The combination also carries risks of side effects from multiple drugs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

gastric adenocarcinoma gastric neoplasm gastroesophageal junction adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shandong First Medical University Affiliated Cancer Hospital

    RECRUITING

    Jinan, Shandong, China

    Contact Phone: •••-•••-••••