SQUAMOUS CELL CARCINOMA

This study looked at whether adding cetuximab to avelumab works better than avelumab alone for people with advanced head and neck cancer that has come back or spread. The cancer in these patients is not curable, and average survival is less than a year. The trial first checked th…

This small early-phase trial tested an experimental drug called rigosertib in just 2 people with a rare blistering skin disease (recessive dystrophic epidermolysis bullosa) who also had advanced skin cancer. The goal was to see if the drug could shrink tumors and whether it was s…

This study tested a new device that delivers targeted radiation to early-stage basal and squamous cell skin cancers. Thirty-six people aged 60 and older received treatment, and researchers tracked how well the cancer was controlled, cosmetic results, and quality of life. The goal…

This study tested whether the drug everolimus can reduce new skin cancers in heart transplant patients who already had skin cancer. 175 participants received either everolimus or standard immunosuppressants. The goal was to see if everolimus lowers the number of new skin tumors n…

This early-phase trial tested a combination of two drugs — IRX-2 and durvalumab — in 19 people with advanced head and neck cancer that could not be cured by standard treatments. The goal was to see if the combination was safe and could boost the immune response inside tumors. The…

This early-phase trial tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiation is safe and effective for people with advanced head and neck cancer. 59 participants received pembrolizumab before, during, and after their regular treatment. The goal was…

This study tested whether quercetin, a natural substance found in some foods, could help prevent a type of mouth cancer in people with Fanconi anemia, a rare genetic condition that raises cancer risk. 48 participants took quercetin to see if it reduced certain cell changes linked…

This study tested whether a daily application of diclofenac gel, a common anti-inflammatory drug, can reverse certain biomarkers in the skin that are linked to non-melanoma skin cancer. Twenty-four adults at risk for skin cancer applied the gel for 30 days, and researchers took s…

This study looked at whether giving people personalized information about their genetic risk for melanoma could encourage them to protect themselves from the sun. Over 2,000 adults received either standard sun safety tips or tailored advice based on their DNA. Researchers then tr…

This study tested whether adding thalidomide to glutamine can delay the onset of severe mouth sores caused by radiation therapy. 138 oral cancer patients were randomly assigned to receive either the combination or glutamine alone during their radiation treatment. The main goal wa…

This study tested a simple photo-based method to measure changes in nose shape and size after skin cancer surgery. Researchers took before-and-after photos of 68 patients who had surgery for common skin cancers. The goal was to see if this photographic approach could be a reliabl…