SQUAMOUS CELL CARCINOMA
Clinical trials for SQUAMOUS CELL CARCINOMA explained in plain language.
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MRI-Guided radiation aims to zap tumors, spare healthy tissue
Disease control OngoingThis study is testing whether using MRI scans during radiation treatment can help doctors better target head and neck cancer tumors while reducing damage to nearby healthy organs. The trial involves 25 patients and aims to personalize the radiation dose based on how the tumor res…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New injection tested to shrink skin cancer before removal
Disease control OngoingThis early-stage study is testing whether injecting an experimental therapy called RP1 directly into skin cancer tumors can help shrink them before surgical removal. The trial will enroll up to 12 adults with resectable cutaneous squamous cell carcinoma to assess safety and see i…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Sherrif Ibrahim • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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Could a gentler treatment work for HPV throat cancer?
Disease control OngoingThis trial is for people with early-stage throat cancer caused by HPV who are not heavy smokers. It compares the current standard treatment (high-dose radiation with chemotherapy) to a new approach using lower-dose radiation combined with an immunotherapy drug called nivolumab. T…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New drug combo aims to reboot immune system against tough head & neck cancers
Disease control OngoingThis study is testing if adding an experimental drug called bavituximab to an approved immunotherapy (pembrolizumab) can help control advanced head and neck cancer that has started growing again after prior immunotherapy. It is for adults whose cancer has spread or returned and w…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Modified virus tested to attack tough esophageal cancers
Disease control OngoingThis early-stage study is testing the safety of adding a specially designed virus (OBP-301) to standard chemotherapy and radiation for patients with advanced esophageal or gastroesophageal cancer who are not candidates for surgery. The virus is meant to infect and kill cancer cel…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New injection offers hope for advanced skin cancer patients
Disease control OngoingThis study is testing whether an injection treatment can help control advanced skin cancer that has returned or spread, or that cannot be removed by surgery. It involves 19 Japanese patients with this specific type of skin cancer. The main goal is to see if the treatment shrinks …
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Mar 12, 2026 13:52 UTC
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Doctors test less radiation for HPV throat cancer to reduce harsh side effects
Disease control OngoingThis study is testing whether using lower doses of radiation to a smaller area of the head and neck can still effectively control cancer after surgery for HPV-positive throat cancer. The goal is to see if this 'de-intensified' approach can maintain good cancer control while poten…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Mar 12, 2026 13:50 UTC
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Research probes survival gap for native americans on cancer immunotherapy
Knowledge-focused OngoingThis study looks back at medical records to understand how well immunotherapy cancer drugs work for American Indian patients compared to White patients. Researchers will analyze survival times, side effects, and cancer-related deaths in 72 patients who were treated between 2015 a…
Matched conditions: SQUAMOUS CELL CARCINOMA
Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC