SQUAMOUS CELL CARCINOMA

This study tests an experimental drug called RP1 that is injected directly into skin cancer tumors. The goal is to see if it can shrink or eliminate the cancer before surgery. About 12 adults with resectable cutaneous squamous cell carcinoma will participate. The main focus is sa…

This study looks at whether giving lower doses of radiation to a smaller area after robotic surgery can still prevent HPV-related throat cancer from coming back. About 150 adults with early-stage cancer will receive this gentler treatment. The goal is to maintain cancer control w…

This study tests whether adding bavituximab to pembrolizumab can help shrink tumors or slow cancer growth in people with advanced head and neck cancer that has not responded to standard treatments. The trial enrolled 7 adults whose cancer had worsened after prior immunotherapy. T…

This study looks at whether a lower dose of radiation combined with the immunotherapy drug nivolumab can control early-stage HPV-positive throat cancer as well as the standard higher-dose radiation plus chemotherapy (cisplatin). The trial includes 384 non-smoking patients with ea…

This study tests a new drug combination (pembrolizumab plus berahyaluronidase alfa) given as a shot under the skin for Japanese patients with advanced squamous cell skin cancer that has come back, spread, or cannot be removed with surgery. The main goal is to see if the treatment…

This early-phase trial tests whether adding a cancer-killing virus (OBP-301) to standard chemotherapy and radiation is safe for people with advanced esophageal or gastroesophageal cancer who cannot have surgery. The virus is designed to infect and destroy tumor cells. The study e…

This study looks back at medical records of 72 American Indian adults with cancers like lung, melanoma, and kidney who received immunotherapy. Researchers compare their outcomes, such as cancer progression and side effects, to those of White patients. The goal is to spot any diff…