Mouth rinse could ease painful radiation side effects for head and neck cancer patients

NCT ID NCT07697287

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This trial tests Gelclair, a mouth rinse that forms a protective coating over the mouth's lining, to see if it eases the painful mouth sores (oral mucositis) caused by radiation therapy for head and neck cancer. The study enrolls adults with squamous cell carcinoma who will receive at least 60 Gy of radiation over 6-7 weeks. Researchers will measure how well patients tolerate the rinse and whether it improves their quality of life compared to the standard rinse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Gelclair (oral mouth rinse)
What this could lead to
If effective, Gelclair could offer a simple, safe way to reduce mouth pain during radiation, making eating and drinking easier for patients.
What could go wrong
This is a small feasibility study, not a large trial. It may not prove Gelclair works better than standard rinses, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Juravinski Cancer Centre

    Hamilton, Ontario, L8V 5C2, Canada

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