SQUAMOUS CELL CARCINOMA
Clinical trials for SQUAMOUS CELL CARCINOMA explained in plain language.
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New skin patch could speed recovery after skin cancer removal
Disease control Not yet recruitingThis trial tests whether a new skin graft substitute (CAMP) plus standard wound care helps wounds heal faster after Mohs surgery for skin cancer compared to standard care alone. About 160 adults who have had Mohs surgery for a skin cancer will be randomly assigned to receive eith…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE4 • Sponsor: BioLab Holdings • Aim: Disease control
Last updated Jul 12, 2026 00:00 UTC
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New combo aims to tame HPV throat cancer with fewer side effects
Disease control Not yet recruitingThis early-phase trial tests whether a new drug (ATRN-119) combined with a single, precise dose of radiation to the neck can safely and effectively treat early-stage HPV-positive throat cancer before surgery. About 35 participants will take the drug daily for 10 days and receive …
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Genetically modified cells injected into mouth lesions to stop cancer before it starts
Disease control Not yet recruitingThis early-phase trial tests whether specially engineered immune cells (NK cells) can safely treat high-risk precancerous spots in the mouth. The cells are injected directly into the lesions and are designed to target a protein called TROP2, while also resisting signals that norm…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New chemo cocktail aims to tame advanced head and neck cancer
Disease control Not yet recruitingThis phase 2 trial tests whether a combination of two chemotherapy drugs, cyclophosphamide and etoposide, can control advanced head and neck cancer in adults who have already tried standard treatment. 120 participants will receive either the drug combo or methotrexate for 6 month…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute, Egypt • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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New drug duo aims to shrink tough head and neck tumors
Disease control Not yet recruitingThis study tests whether adding fianlimab to the standard cemiplimab plus chemotherapy can better shrink tumors in adults with advanced HPV-positive head and neck cancer. About 90 participants will receive either the two-drug or three-drug combination before radiation. The goal i…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Glowing cancer cells: a new way to see tumors during surgery?
Diagnosis Not yet recruitingThis trial tests whether two imaging agents, Panitumumab-IRDye800 and [18F]NOTA-ABY-030, are safe and useful for helping surgeons identify head and neck tumors and cancer-containing lymph nodes during surgery. Adults with head and neck squamous cell carcinoma who are scheduled fo…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Diagnosis
Last updated Aug 05, 2026 00:00 UTC
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AI-Powered endoscopy aims to spot head and neck cancer earlier
Diagnosis Not yet recruitingThis study will test artificial intelligence algorithms that analyze video from routine endoscopies of the head and neck. The AI will try to detect, classify (benign vs. malignant), and outline lesions, comparing its performance to doctors and lab results. About 283 adults with s…
Matched conditions: SQUAMOUS CELL CARCINOMA
Sponsor: Istituto Italiano di Tecnologia • Aim: Diagnosis
Last updated Jun 27, 2026 12:35 UTC
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Botox before the knife: could a Pre-Surgery injection lead to Better-Looking scars?
Symptom relief Not yet recruitingThis trial tests whether injecting Botox (abobotulinumtoxin-A) into the forehead muscles just before paramedian forehead flap surgery can improve the cosmetic appearance of the resulting scar. Adults with nasal skin cancer defects needing this reconstruction are randomly assigned…
Matched conditions: SQUAMOUS CELL CARCINOMA
Phase: PHASE4 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated Jul 24, 2026 00:00 UTC