New chemo cocktail aims to tame advanced head and neck cancer
NCT ID NCT07361133
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 2 trial tests whether a combination of two chemotherapy drugs, cyclophosphamide and etoposide, can control advanced head and neck cancer in adults who have already tried standard treatment. 120 participants will receive either the drug combo or methotrexate for 6 months. Researchers will track tumor size, symptoms, and side effects to see if this approach is effective and safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cyclophosphamide and etoposide (chemotherapy drugs)
- What this could lead to
- If it works, this could offer a new treatment option for patients with advanced head and neck cancer who have run out of standard options.
- What could go wrong
- This is a small, early-phase trial (phase 2) with only 120 participants. The drugs may not work better than existing treatments, and side effects from chemotherapy can be serious.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
National Cancer Institute
Cairo, Cairo Governorate, 11796, Egypt
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Other studies related to the condition(s) this trial covers.
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