Immunotherapy duo shows promise against advanced oral cancer

NCT ID NCT05681039

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 29 times

Summary

This study tests whether giving two immunotherapy drugs (tiragolumab and atezolizumab) before and after standard surgery and chemoradiation can help control advanced oral cancer. It includes 29 adults with newly diagnosed, stage 3-4 oral cavity squamous cell carcinoma that has a specific protein (PD-L1). The main goal is to see how many patients have a major reduction in tumor cells after the drugs.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.