Immunotherapy duo shows promise against advanced oral cancer in early trial

NCT ID NCT05681039

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 22 times

Summary

This study tests whether giving two immunotherapy drugs (tiragolumab and atezolizumab) before and after standard surgery and chemoradiation can better control advanced oral cancer. It includes 29 adults with newly diagnosed stage 3-4 oral cavity squamous cell carcinoma that has a specific protein (PD-L1). The main goal is to see if the tumor shrinks significantly after the drugs are given before surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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