Immunotherapy boosts standard treatment for head and neck cancer in early trial

NCT ID NCT02586207

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tested whether adding the immunotherapy drug pembrolizumab to standard chemoradiation is safe and effective for people with advanced head and neck cancer. 59 participants received pembrolizumab before, during, and after their regular treatment. The goal was to see if this combination could improve tumor shrinkage and control the disease, while monitoring side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sanford Health Cancer Center

    Sioux Falls, South Dakota, 57104, United States

  • Sanford-Bismarck Medical Center

    Bismarck, North Dakota, 58501, United States

  • Sanford-Roger Maris Cancer Center

    Fargo, North Dakota, 58122, United States

  • UCSD Moores Cancer Center

    La Jolla, California, 92093-0698, United States

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