SOLID TUMOR, ADULT
Clinical trials for SOLID TUMOR, ADULT explained in plain language.
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First patients test new pill aimed at slowing advanced cancers
Disease control CompletedThis was a first-in-human study to test the safety and find the right dose of a new oral drug, JNJ-64619178, for people with advanced cancers that have not responded to other treatments. It involved 114 adults with specific advanced solid tumors, non-Hodgkin lymphoma, or a type o…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Apr 01, 2026 21:26 UTC
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Experimental cancer drug tested in patients out of options
Disease control CompletedThis early-stage study tested a new drug called DCR-STAT3 in adults with advanced solid tumors that had stopped responding to standard treatments. The main goal was to check the drug's safety and how the body processes it in 26 participants. Researchers also looked for early sign…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1 • Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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First human test of new cancer drug shows safety profile
Disease control CompletedThis first-in-human study tested the safety of a new oral drug called EVT801 in 32 adults with advanced solid tumors that hadn't responded to standard treatments. Researchers aimed to find the highest safe daily dose that could be used in future studies. The trial also looked at …
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1 • Sponsor: Kazia Therapeutics Limited • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New cancer drug targets immune system in early human trial
Disease control CompletedThis was an early-stage study to test a new drug called DF9001 in people with advanced solid tumors that have spread, returned, or cannot be removed by surgery. The main goals were to find a safe dose and see how the body processes the drug. Researchers also looked for early sign…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Dragonfly Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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Experimental drug tested for Hard-to-Treat cancers
Disease control CompletedThis study tested an experimental drug called leronlimab in patients with advanced solid tumors that had a specific marker (CCR5+). The main goals were to check the drug's safety and see if it could help control the cancer. Patients received weekly injections of leronlimab, often…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE2 • Sponsor: CytoDyn, Inc. • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New cancer drug trial targets immune system to fight advanced tumors
Disease control CompletedThis study tested a new drug called DF1001, which is designed to guide the body's natural immune cells to attack cancer. It involved 270 adults with advanced solid tumors that had a specific marker called HER2. The trial first found a safe dose and then tested DF1001 alone and in…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Dragonfly Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New cancer treatment trial targets multiple advanced tumors
Disease control CompletedThis study tested a new immunotherapy combination (ICT01 plus low-dose IL-2) for people with advanced solid tumors that had stopped responding to standard treatments. The trial aimed to determine if this combination was safe and could help control cancer growth. It involved 56 pa…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1, PHASE2 • Sponsor: ImCheck Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:34 UTC
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First patients test experimental cancer drug in early safety trial
Disease control CompletedThis first-in-human study tested the safety of a new cancer drug called DF6215, both alone and combined with an existing immunotherapy (pembrolizumab), in adults with advanced solid tumors that couldn't be removed by surgery, had returned, or had spread. The main goals were to fi…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1 • Sponsor: Dragonfly Therapeutics • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Scientists test new Two-Drug attack on tough cancers
Disease control CompletedThis early-stage study tested the safety and initial effects of combining two oral drugs, BGB-283 and PD-0325901, in adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and see if the drug combination could…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1 • Sponsor: BeiGene • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Old drugs, new trick: can leukemia meds supercharge cancer immunotherapy?
Disease control CompletedThis study tested if adding two older leukemia drugs (6MP and 6TG) to a modern immunotherapy drug (atezolizumab) could help control advanced solid tumors. The idea was that the older drugs might cause more mutations in the cancer, making it more visible to the immune system. It i…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1, PHASE2 • Sponsor: Kristoffer Rohrberg • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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First patients test new cancer drug as last hope
Disease control CompletedThis was the first-ever study in people of a new cancer drug called GEN1056. It tested the drug's safety and aimed to find the right dose for future studies in 26 adults with advanced solid tumors that had stopped responding to standard treatments. The main goal was to see how sa…
Matched conditions: SOLID TUMOR, ADULT
Phase: PHASE1 • Sponsor: Genmab • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC