New cancer drug shows promise in early human testing

NCT ID NCT03573310

First seen Nov 01, 2025 · Last updated May 04, 2026 · Updated 22 times

Summary

This early-stage study tested a new drug called JNJ-64619178 in 114 adults with advanced cancers (like lymphoma, solid tumors, or myelodysplastic syndromes) that had not responded to other treatments. The main goal was to find the safest dose and check for side effects. The drug works by blocking a protein that helps cancer cells grow.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Carmel Medical Center

    Haifa, 34362, Israel

  • Clinica Univ. de Navarra

    Pamplona, 31008, Spain

  • Florida Specialist and Cancer Institute

    Sarasota, Florida, 34232, United States

  • Goethe Universität Frankfurt

    Frankfurt am Main, 60590, Germany

  • Hadassah Medical Center

    Jerusalem, 9112001, Israel

  • Hosp Clinico Univ de Salamanca

    Salamanca, 37007, Spain

  • Hosp Univ Fund Jimenez Diaz

    Madrid, 28040, Spain

  • Hosp Univ Vall D Hebron

    Barcelona, 08035, Spain

  • Hosp. Univ. Germans Trias I Pujol

    Badalona, 08916, Spain

  • Hosp. Virgen Del Rocio

    Seville, 41013, Spain

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Ohio State University

    Columbus, Ohio, 43210, United States

  • Princess Margaret Cancer Centre University Health Network

    Toronto, Ontario, M5G1Z5, Canada

  • St. Paul's Hospital

    Vancouver, British Columbia, V6E 1M7, Canada

  • Tel Aviv Sourasky MC

    Tel Aviv, 6423906, Israel

  • Universitaetsklinikum Duesseldorf

    Düsseldorf, 40225, Germany

  • Universitaetsklinikum Leipzig

    Leipzig, 04103, Germany

  • University of Texas, MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.