SOCIAL ANXIETY DISORDER

This study tests whether a computer-assisted tool helps mental health providers in rural VA clinics deliver cognitive behavioral therapy (CBT) more effectively for depression and anxiety. About 34 therapists and 167 veterans will take part. Therapists are randomly assigned to use…

This Phase 3 trial tested a once-daily extended-release capsule called centanafadine in 315 adults with both ADHD and anxiety (generalized or social anxiety). For 8 weeks, participants received either the drug or a placebo. The study measured changes in ADHD symptoms using a clin…

This pilot study tested a new type of brain stimulation, called accelerated intermittent theta burst stimulation (aiTBS), for people with anxiety disorders or PTSD. Fifteen participants received the non-invasive treatment targeting a novel brain area. The study measured changes i…

This study looked at whether holding powerful poses before exposure therapy can increase testosterone levels and make treatment for social anxiety more effective. 73 adults with social anxiety disorder participated. The goal was to see if this simple change could help people feel…

This study tested whether D-cycloserine, an antibiotic that helps the brain unlearn fear, can improve cognitive-behavioral therapy (CBT) for social anxiety. 152 adults with social anxiety took either D-cycloserine or a placebo before or after their therapy sessions. Researchers w…

This study looked at whether different intensities of exercise can reduce anxiety in adults with anxiety disorders. 110 sedentary adults with high anxiety sensitivity were assigned to either low-intensity exercise or a program that gradually increased to high-intensity exercise o…

This study tested whether a single dose of BNC210 can quickly reduce anxiety in people with social anxiety disorder. 370 adults took either the drug or a placebo before a public speaking challenge and rated their distress. The goal is to see if BNC210 works as an as-needed treatm…

This study tested whether a 6-week group therapy program (cognitive behaviour therapy) could help reduce anxiety and stress in pregnant women and new mothers. 72 women from Manitoba, Canada, who were pregnant or within 12 months postpartum and had an anxiety disorder took part. T…

This study tested an internet-based cognitive behavioral therapy (CBT) program called AMTE for adolescents with anxiety and depression. Sixty teens were randomly assigned to either the online program or a control group. The goal was to see if the program could reduce symptoms of …

This study tested a new way to help people with social anxiety by training them to replace negative thoughts with positive or neutral ones. 54 university students with high social anxiety were split into two groups: one practiced proactive thought control with AI feedback, the ot…

This study tested whether an 8-session group cognitive behavioral therapy program can reduce social anxiety in adolescents aged 12 to 17. Thirty-four teens with social anxiety disorder took part, comparing the group therapy to standard psychoeducation. The goal was to see if the …

This study tested an online compassion-focused therapy for 49 teens with social anxiety disorder. The therapy aimed to help them manage emotions and reduce anxiety by teaching self-compassion. Researchers also measured heart rate to see if it changed with therapy. The goal was to…

This study tested a new oral drug called EMP-01 in 70 adults with social anxiety disorder. Participants received either EMP-01 or a placebo for a short time to see if the drug is safe and helps reduce anxiety in social situations. The main goal was to check for side effects, whil…

This pilot study tested a text-message intervention to help veterans with social anxiety reduce 'safety behaviors' — things like avoiding eye contact or rehearsing sentences — that get in the way of work and social life. 23 veterans in a work therapy program received text prompts…

This study tested whether cannabidiol (CBD), a compound from the cannabis plant, can reduce symptoms of social anxiety disorder. Sixty adults with moderate to severe social anxiety took either a high dose of CBD, a lower dose, or a placebo pill twice daily for three weeks. Resear…

This study tested whether a gentle, non-invasive brain stimulation technique called HD-tDCS could reduce negative thinking patterns in 74 young adults with social anxiety. Participants received 10 sessions over 5 days, targeting a brain area linked to emotion control. The goal wa…

This study tested whether text message reminders to stop 'safety behaviors' (like checking mirrors or seeking reassurance) could ease appearance concerns. 401 adults with body dysmorphic disorder, social anxiety, or eating disorders were split into two groups: one received text p…

This Phase 3 trial tested whether a low-dose nasal spray called PH94B can quickly reduce anxiety in adults with social anxiety disorder when they have to speak in public. 224 participants used the spray or a placebo 20 minutes before a short speech and rated their distress. The s…

This study tested a new program called Adjunctive Family-Cognitive Behavioral Therapy (AF-CBT) for veterans with anxiety disorders. It involved 48 veterans and their family members to see if adding family support to standard therapy was acceptable and helpful. The main goal was t…

This study looks at how the brains of children aged 9 to 12 with anxiety disorders respond to making mistakes. Researchers measure two types of brain activity: one after an error and one after a balance disturbance. Half of the children will use a 45-minute computer program desig…

This study looked at whether brain activity patterns can predict how well people with major depression or social anxiety respond to cognitive behavioral therapy (CBT). Over 200 participants were randomly assigned to 12 weeks of CBT or supportive therapy. Researchers measured brai…

This study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages, including children as young as 8, to track patterns of these conditions over time.…

This study looked at whether exercise helps adults with high anxiety and anxiety disorders (like generalized anxiety, panic, or social anxiety) better learn to unlearn fear. 54 participants either exercised or sat quietly after a fear-extinction task. Researchers measured skin sw…

This study tested whether real-time fMRI neurofeedback can help people with anxiety disorders better regulate their emotions. 21 participants practiced cognitive reappraisal while receiving feedback on their prefrontal cortex activity. The goal was to understand the brain mechani…

This study followed 559 children and teens ages 6 to 19 in the McLean Anxiety Mastery Program to see if their anxiety and depression improved with treatment. Researchers compared patients who received treatment to those on a waitlist and checked if gains lasted three months after…