New pill could take the edge off social anxiety on the spot

NCT ID NCT06510504

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single dose of BNC210 can quickly reduce anxiety in people with social anxiety disorder. 370 adults took either the drug or a placebo before a public speaking challenge and rated their distress. The goal is to see if BNC210 works as an as-needed treatment for social anxiety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BNC210

What this could lead to

If successful, BNC210 could offer a fast-acting, on-demand option to ease anxiety during social situations like public speaking.

What could go wrong

This is a completed Phase 3 trial, but results are not yet public. The drug may not work better than placebo, and side effects are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

social phobia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AFFIRM-1 Study Site

    Encino, California, 91316, United States

  • AFFIRM-1 Study Site

    La Jolla, California, 92037, United States

  • AFFIRM-1 Study Site

    Los Angeles, California, 90025, United States

  • AFFIRM-1 Study Site

    Oceanside, California, 92056, United States

  • AFFIRM-1 Study Site

    San Diego, California, 92103, United States

  • AFFIRM-1 Study Site

    San Jose, California, 95124, United States

  • AFFIRM-1 Study Site

    Sherman Oaks, California, 91403, United States

  • AFFIRM-1 Study Site

    Temecula, California, 92591, United States

  • AFFIRM-1 Study Site

    Jacksonville, Florida, 32256, United States

  • AFFIRM-1 Study Site

    Lauderhill, Florida, 33319, United States

  • AFFIRM-1 Study Site

    Miami Lakes, Florida, 33016, United States

  • AFFIRM-1 Study Site

    Orlando, Florida, 32801, United States

  • AFFIRM-1 Study Site

    Tampa, Florida, 33607, United States

  • AFFIRM-1 Study Site

    Decatur, Georgia, 30030, United States

  • AFFIRM-1 Study Site

    Boston, Massachusetts, 02114, United States

  • AFFIRM-1 Study Site

    Boston, Massachusetts, 02131, United States

  • AFFIRM-1 Study Site

    Princeton, New Jersey, 08540, United States

  • AFFIRM-1 Study Site

    Brooklyn, New York, 11229, United States

  • AFFIRM-1 Study Site

    Charlotte, North Carolina, 28211, United States

  • AFFIRM-1 Study Site

    Media, Pennsylvania, 19063, United States

  • AFFIRM-1 Study Site

    Austin, Texas, 78737, United States