SEVERE ASTHMA

This study tests a procedure called bronchial thermoplasty (BT) for people with severe asthma that still causes attacks despite using biologics or other strong medications. BT uses a thin tube to deliver heat to the airways to reduce their overreaction. The goal is to see if BT c…

This study tests an experimental drug called GB-0895 in about 786 adults and teens (ages 12-80) with severe asthma that isn't controlled by standard inhalers and other medications. Participants will receive either GB-0895 or a placebo as a shot every 6 months for a year. The goal…

This study looks at whether people with severe asthma can safely cut down on their usual maintenance medications if they are also taking the drug tezepelumab. The goal is to see if patients can reduce or stop some of their daily inhalers and pills while still keeping their asthma…

This study tests a new drug called GB-0895 for people aged 12 to 80 with severe asthma that is not controlled by standard inhalers and other medications. Participants will receive either GB-0895 or a placebo injection every 6 months for a year. The main goal is to see if GB-0895 …

This study tests a drug called benralizumab for people with severe asthma and a fungal lung condition called ABPA. The goal is to see if it can reduce the number of asthma attacks that need steroids and improve quality of life. About 20 adults will take part. This is not a cure, …

This study tests a new medicine called FB704A for adults with severe asthma. The goal is to see if it is safe and can help control asthma symptoms. About 20 people will receive either the drug or a placebo over 8 weeks, with follow-up for 12 more weeks. Participants must have poo…

This study looks at how mucus plugs block airways in people with severe asthma. Using special xenon MRI scans, researchers will check lung function in blocked areas before and after starting biologic therapy. The goal is to understand how these plugs affect breathing and how trea…

This study is creating a large database and biobank from 2200 patients with chronic inflammatory diseases like lupus, multiple sclerosis, and severe asthma. Researchers will track disease activity, quality of life, and treatment responses over time. The goal is to identify new ma…

This study aims to find out how many adults with severe asthma in Thailand achieve remission and what factors might be linked to it. Researchers will collect data from 230 participants through questionnaires, breathing tests, and a blood test. No treatment is given; the goal is s…

This study is a registry that collects health information from 714 adults with severe asthma across Canada over five years. Researchers will track things like lung function, asthma attacks, and treatments to understand how well current therapies work. The goal is to use this real…

This study will look at 5,000 adults in Russia who have severe asthma that is not well controlled. Researchers will collect information on the medicines patients are already taking and their health details. The goal is to better understand current treatment patterns and patient c…

This study looks at how mucus plugs in the lungs of people with severe asthma affect their ability to breathe. Researchers will use special MRI scans to see air flow in areas blocked by mucus. Five adults with severe asthma will be scanned before and after starting a new biologic…

This study is a registry that will collect information from 5,000 people with severe asthma. Researchers want to learn about patients' health, how well they follow their treatments, and how biologic drugs work in everyday life. The goal is to improve long-term care and understand…