SEVERE ASTHMA
Clinical trials for SEVERE ASTHMA explained in plain language.
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BREAKTHROUGH: asthma drug may let patients cut inhaler use without losing control
Disease control OngoingThis study tests if tezepelumab, a monthly injection, can help people with severe asthma safely reduce their daily maintenance inhaler (SYMBICORT) while still keeping their asthma under control. About 326 adolescents and adults will be followed for up to 72 weeks. The goal is to …
Matched conditions: SEVERE ASTHMA
Phase: PHASE3 • Sponsor: AstraZeneca • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New asthma drug shows promise in Long-Term trial
Disease control OngoingThis study looks at the long-term safety and effectiveness of a drug called verekitug for adults with severe asthma. It includes 396 people who already finished the earlier VALIANT study. Researchers will track side effects and how often asthma attacks happen over time.
Matched conditions: SEVERE ASTHMA
Phase: PHASE2 • Sponsor: Upstream Bio Inc. • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New asthma drug shows promise in Real-World study
Disease control OngoingThis study looks at how well tezepelumab works for people aged 12 and older with severe asthma in Russia. It tracks symptom control over 52 weeks using patient questionnaires. The goal is to understand the real-world benefits of this treatment.
Matched conditions: SEVERE ASTHMA
Sponsor: AstraZeneca • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Scientists track severe asthma in kids to uncover hidden patterns
Knowledge-focused OngoingThis study follows 362 children with severe asthma to find out what makes their asthma worse and how it changes as they grow up. Researchers will look at medical history, symptoms, and test results to identify risk factors and long-term outcomes. The goal is to better understand …
Matched conditions: SEVERE ASTHMA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 17, 2026 06:47 UTC
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AI could spot severe asthma faster than doctors
Knowledge-focused OngoingThis study uses artificial intelligence (AI) and natural language processing (NLP) to automatically find people with moderate to severe asthma by scanning electronic health records. Researchers will compare the AI's findings to diagnoses made by asthma specialists to see how accu…
Matched conditions: SEVERE ASTHMA
Sponsor: San Diego State University • Aim: Knowledge-focused
Last updated May 17, 2026 06:46 UTC
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Spit test could predict drug response in rare lung disease
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks for proteins in blood, saliva, and sputum that can show organ damage and predict how well patients with EGPA (a rare inflammatory disease) or severe asthma respond to the drug mepolizumab. Researchers will analyze samples from 90 participants before and after sta…
Matched conditions: SEVERE ASTHMA
Phase: PHASE4 • Sponsor: Azienda Ospedaliero Universitaria di Cagliari • Aim: Knowledge-focused
Last updated May 13, 2026 16:03 UTC
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Asthma cell study in kids halted before it began
Knowledge-focused TerminatedThis study planned to compare immune cells called type 2 innate lymphoid cells (ILC2) in children with severe asthma versus non-asthmatic children. Researchers wanted to see if these cells are higher in asthmatic children and if they relate to other markers of airway inflammation…
Matched conditions: SEVERE ASTHMA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated May 13, 2026 16:01 UTC