SEVERE ASTHMA

This study tests whether the drug tezepelumab can help people with severe asthma reduce their daily maintenance inhaler dose without losing control of their asthma. About 326 adolescents and adults will receive tezepelumab injections and then try to step down their usual inhaler …

This study is for adults with severe asthma who finished the earlier VALIANT trial. It tests the long-term safety and effectiveness of verekitug, a drug given as a shot. About 396 people are taking part. The main goal is to see if verekitug is safe over time and if it can reduce …

This study follows 125 people aged 12 and older with severe asthma who are starting tezepelumab in Russia. Over 52 weeks, researchers will track how well their symptoms are controlled using a standard questionnaire. The goal is to see how the drug works outside of clinical trials…

This study looks back at medical records of 197 adults in Israel who started benralizumab for severe asthma between 2019 and 2024. Researchers will count how many asthma attacks (exacerbations) patients had before and after starting the drug. The goal is to see how well benralizu…

This study looks at how dupilumab, a drug for severe asthma, is actually used by patients in France. Researchers will analyze health records of about 35,000 people to describe their characteristics, healthcare costs, and steroid use before and after starting the drug. The goal is…

This study watches 100 people with severe asthma who are taking biologic drugs. Researchers measure how the body reacts to the drug and whether it affects asthma attacks. The goal is to learn more about drug effectiveness and safety.

This study uses artificial intelligence and natural language processing to scan electronic health records and identify people with severe asthma. Researchers will compare the AI's findings to diagnoses made by doctors. The goal is to improve how severe asthma is detected and make…

This study aims to find biological markers in blood, saliva, and sputum that can predict how well patients with EGPA (a rare inflammatory disease) and severe asthma respond to the drug mepolizumab. Researchers will analyze proteins in these samples before and after treatment to u…

This study was designed to compare certain immune cells (called ILC2) in the lungs of children with severe asthma versus children without asthma. The goal was to see if these cells are higher in asthmatic children and if they relate to other markers of airway inflammation. Howeve…

This study follows 362 children with severe asthma to identify different types of the disease and what makes it worse. Researchers will track their health from childhood into adulthood to see how asthma changes over time. The goal is to find risk factors and improve treatment str…