Breakthrough asthma drug may let patients ditch puffers

NCT ID NCT07363642

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 trial is testing whether people with severe asthma who take the drug Tezepelumab can safely cut back on their other daily asthma medications without losing control of their symptoms. About 400 participants aged 12 to 80 will be enrolled. The goal is to see if they can reduce or stop certain maintenance drugs while staying well.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Tezepelumab

What this could lead to

If successful, this could show that many severe asthma patients can safely reduce their daily controller medications while maintaining good symptom control.

What could go wrong

This is a single-arm study without a placebo group, so results may be less definitive. Reducing medication could lead to worsening asthma in some patients, and benefits may not apply to all types of severe asthma.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma chronic asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SEVERE ASTHMA

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Beijing, 100020, China
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Beijing, 100191, China
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Beijing, 100730, China
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Beijing, 100730, China
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Beijing, 102300, China
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Beijing, 10730, China
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Beijing, 211405, China
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Binzhou, 256606, China
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Changsha, 410008, China
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Changsha, 430033, China
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Chengdu, 610041, China
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Chengdu, 610072, China
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Chengdu, 610095, China
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Chengdu, 610500, China
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Chongqing, 400042, China
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Chongqing, 400072, China
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Deyang, 618000, China
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Fuzhou, 350001, China
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Guangzhou, 510080, China
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Guangzhou, 510100, China
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Guangzhou, 510163, China
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Guangzhou, 510180, China
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Guangzhou, 510280, China
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Guangzhou, 510515, China
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Guangzhou, 510620, China
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Guiyang, 510630, China
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Hangzhou, 310003, China
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Hangzhou, 310006, China
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Hangzhou, 310016, China
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Hefei, 230061, China
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Hefei, 230601, China
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Hohhot, 010017, China
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Jiangmen, 529000, China
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Jinan, 250012, China
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Jinan, 250014, China
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Jinan, 250021, China
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Jining, 272006, China
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Kunming, 650032, China
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Leshan, 614000, China
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Linyi, CN-276003, China
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Luzhou, 646000, China
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Meizhou, 514700, China
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Mianyang, 621000, China
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Nanchang, 330006, China
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Nanjing, 210029, China
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Nanjing, 211100, China
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Nanning, 530000, China
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Ningbo, 315010, China
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Quanzhou, 362000, China
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Shanghai, 200000, China
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Shanghai, 200003, China
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Shanghai, 200025, China
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Shanghai, 200032, China
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Shanghai, 200433, China
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Shanghai, 310000, China
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Shantou, 515041, China
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Shenyang, 110001, China
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Shenzhen, 518020, China
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Shenzhen, 518036, China
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Shijiazhuang, 054001, China
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Suining Shi, 629000, China
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Suzhou, 215006, China
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Taiyuan, 030001, China
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Taiyuan, 030032, China
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Tianjin, 300192, China
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Weifang, 261000, China
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Wenzhou, 325027, China
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Wuhan, 430030, China
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Wuhan, 430060, China
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Wuxi, 214023, China
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Xi'an, 710061, China
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Zhangzhou, 363099, China
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Zhanjiang, 524004, China
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Zhengzhou, 450003, China
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Zhengzhou, 450007, China
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Zhongshan, 528403, China