SEVERE AORTIC STENOSIS
Clinical trials for SEVERE AORTIC STENOSIS explained in plain language.
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New heart valve trial aims to improve survival in severe aortic stenosis
Disease control Recruiting nowThis study is testing the safety and effectiveness of the RENATUS transcatheter aortic valve system in 800 people with severe aortic stenosis (a narrowed heart valve). Participants receive the valve through a less invasive procedure. The main goal is to see how many people surviv…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Beijing Balance Medical Technology Co., Ltd • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Heart valve study seeks best blood thinner to prevent clots
Disease control Recruiting nowThis study compares aspirin versus clopidogrel to prevent small blood clots on the new heart valve in people who have had a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. About 254 participants will take both medicines for 4 weeks, then continue with ju…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Yonsei University • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New heart valve study aims to improve safety in severe aortic stenosis patients
Disease control Recruiting nowThis study looks at how safe and effective the Navitor heart valve is for people with severe aortic stenosis in everyday medical practice. About 100 participants will get the valve and be followed for 30 days. The main goals are to see how many survive and whether the valve leaks…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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One stitch or two? new trial aims to simplify heart valve procedure
Disease control Recruiting nowThis study looks at whether using one closure device instead of two is just as safe for closing the blood vessel after a minimally invasive heart valve replacement (TAVR). About 876 people with severe aortic stenosis will take part. The goal is to see if using a single device can…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Heart valve trial asks: is routine artery testing before TAVI unnecessary?
Disease control Recruiting nowThis study looks at whether people with severe aortic stenosis can safely undergo a valve replacement procedure (TAVI) without first having a coronary angiogram—a test that checks for blocked heart arteries. Currently, most patients get this test before TAVI, but it can cause com…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Rede Optimus Hospitalar SA • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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Heart-Lung machine may shield High-Risk patients during valve procedure
Disease control Recruiting nowThis study tests whether using a heart-lung machine (ECMO) before a complex heart valve replacement can prevent death, cardiac arrest, or emergency surgery in high-risk patients. It includes 30 adults with severe aortic stenosis who are unstable or have tricky heart anatomy. Rese…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Atlantic Health System • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New biomimetic heart valve could change TAVR game
Disease control Recruiting nowThis study compares a new heart valve, DurAVR®, designed to work more like a natural valve, to standard TAVR valves in 1650 people with severe aortic stenosis. Participants are randomly assigned to get the new valve or a standard one and are followed for up to 10 years. The goal …
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Anteris Technologies Ltd. • Aim: Disease control
Last updated May 07, 2026 18:43 UTC
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New CT method could revolutionize heart surgery decisions for aortic stenosis patients
Knowledge-focused Recruiting nowThis study looks at whether adding a special CT scan (CT-FFR) to the usual heart imaging helps doctors make better decisions about opening blocked arteries in people with severe aortic stenosis. About 300 participants will be randomly assigned to get either the standard CT or the…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Yan'an Affiliated Hospital of Kunming Medical University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC