One stitch or two? major trial tests simpler closure for heart valve procedure
NCT ID NCT06173115
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether using one stitch device (Perclose) is as safe and effective as using two to close the leg artery after a minimally invasive heart valve replacement (TAVR) in people with severe aortic stenosis. About 876 participants will be randomly assigned to one of the two methods. The goal is to see if using a single device can reduce costs and procedure time without increasing complications like bleeding or artery damage.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for SEVERE AORTIC STENOSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Beijing Anzhen Hospital, Capital Medical University
RECRUITINGBeijing, China
Contact Email: •••••@•••••
-
Department of Cardiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University
RECRUITINGHangzhou, Zhejiang, 310000, China
Contact
-
Fujian Provincial Hospital
RECRUITINGFuzhou, Fujian, China
Contact Email: •••••@•••••
-
Fuwai Central China Cardiovascular Hospital
RECRUITINGZhengzhou, Henan, China
Contact Email: •••••@•••••
-
Fuwai Hospital, Chinese Academy of Medical Sciences
RECRUITINGBeijing, China
Contact Email: •••••@•••••
-
General Hospital of Northern Theater Command, PLA
RECRUITINGShenyang, Liaoning, China
Contact Email: •••••@•••••
-
Henan Provincial Chest Hospital
RECRUITINGZhengzhou, Henan, China
Contact Email: •••••@•••••
-
Huzhou Central Hospital
RECRUITINGHuzhou, Zhejiang, China
Contact Email: •••••@•••••
-
Nanfang Hospital, Southern Medical University
RECRUITINGGuangzhou, Guangdong, China
Contact Email: •••••@•••••
-
Ningbo Medical Center Li Huili Hospital
RECRUITINGNingbo, Zhejiang, China
Contact Email: •••••@•••••
-
People's Hospital of Xinjiang Uygur Autonomous Region
RECRUITINGÜrümqi, Xinjiang, China
Contact Email: •••••@•••••
-
Qilu Hospital of Shandong University
RECRUITINGJinan, Shandong, China
Contact Email: •••••@•••••
-
Qingdao Municipal Hospital
RECRUITINGQingdao, Shandong, China
Contact Email: •••••@•••••
-
Sichuan Provincial People's Hospital
RECRUITINGChengdu, Sichuan, China
Contact Email: •••••@•••••
-
The Affiliated Hospital of Guangdong Medical University
RECRUITINGZhanjiang, Guangdong, China
Contact Email: •••••@•••••
-
The Affiliated Hospital of Qingdao University
RECRUITINGQingdao, Shandong, China
Contact Email: •••••@•••••
-
The First Affiliated Hospital of Bengbu Medical College
RECRUITINGBengbu, Anhui, China
Contact Email: •••••@•••••
-
The First Affiliated Hospital of Ningbo University
RECRUITINGNingbo, Zhejiang, China
Contact Email: •••••@•••••
-
The First Affiliated Hospital of Wenzhou Medical University
RECRUITINGWenzhou, Zhejiang, China
Contact Email: •••••@•••••
-
The First Affiliated Hospital of Xi'an Jiaotong University
RECRUITINGXi’an, Shanxi, China
Contact Email: •••••@•••••
-
The First Affiliated Hospital, Sun Yat-sen University
RECRUITINGGuangzhou, Guangdong, China
Contact Email: •••••@•••••
-
The First Hospital of Lanzhou University
RECRUITINGLanzhou, Gansu, China
Contact Email: •••••@•••••
-
The Second Xiangya Hospital of Central South University
RECRUITINGChangsha, Hunan, China
Contact Email: •••••@•••••
-
Xiangya Hospital of Central South University
RECRUITINGChangshacun, Henan, China
Contact Email: •••••@•••••
-
Yulin First People's Hospital
RECRUITINGYulin, Guangxi, China
Contact Email: •••••@•••••