SEVERE AORTIC STENOSIS
Clinical trials for SEVERE AORTIC STENOSIS explained in plain language.
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New heart valve procedure offers hope for patients too sick for surgery
Disease control CompletedThis study tested a new way to replace a narrowed heart valve without open-heart surgery. It involved 782 people with severe aortic stenosis who were considered too high-risk for traditional surgery. The procedure, called TAVI, uses a thin tube to place a new valve inside the hea…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Medtronic Cardiovascular • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New balloon shows promise in heart valve procedure
Disease control CompletedThis study tested a balloon catheter called Alwide Plus, used to widen the aortic valve before replacing it in people with severe aortic stenosis. 75 patients took part across multiple hospitals in China. The results showed the balloon was safe and effective for this pre-dilation…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Shanghai MicroPort CardioFlow Medtech Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Iron boost after heart valve procedure shows promise in small trial
Symptom relief CompletedThis study looked at whether a single intravenous iron dose could improve exercise capacity in people with severe aortic stenosis and iron deficiency who were scheduled for a valve replacement. About 100 participants received either iron or a placebo. The main goal was to see if …
Matched conditions: SEVERE AORTIC STENOSIS
Phase: PHASE2 • Sponsor: Oslo University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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Full-Body scan reveals how heart valve disease affects blood flow to organs
Knowledge-focused CompletedThis completed study from RenJi Hospital used a special full-body PET/CT scanner to measure blood flow throughout the body in 34 people: 9 healthy volunteers and 16 patients with severe aortic stenosis and reduced heart function. The goal was to see how blood flow differs between…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: RenJi Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Heart valve replacement safe in patients with enlarged aorta?
Knowledge-focused CompletedThis completed study looked at 101 patients with severe aortic stenosis who had a minimally invasive heart valve replacement (TAVR). Researchers wanted to see if the procedure was safe for patients who also had an enlarged ascending aorta (≥40 mm). They compared outcomes like dea…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: zjq • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC