Full-Body scan reveals how heart valve disease affects blood flow to organs

NCT ID NCT04941248

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study from RenJi Hospital used a special full-body PET/CT scanner to measure blood flow throughout the body in 34 people: 9 healthy volunteers and 16 patients with severe aortic stenosis and reduced heart function. The goal was to see how blood flow differs between healthy people and patients, and how it changes after TAVR (a minimally invasive valve replacement). The study does not test a new drug or treatment, but aims to improve understanding of the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors understand how severe aortic stenosis affects blood flow to organs and how TAVR surgery may improve it.

What could go wrong

This is a small, early-stage imaging study with only 34 participants, so results may not apply to all patients. It does not test a treatment or directly improve health.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

aortic valve stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai jiaotong University School of Medicine, Renji Hospital

    Shanghai, Shanghai Municipality, 200127, China