Heart valve replacement safe in patients with enlarged aorta?
NCT ID NCT07148973
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 101 patients with severe aortic stenosis who had a minimally invasive heart valve replacement (TAVR). Researchers wanted to see if the procedure was safe for patients who also had an enlarged ascending aorta (≥40 mm). They compared outcomes like death rates between those with and without an enlarged aorta. The goal was to gather information to help guide future treatment decisions for this specific group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transcatheter Aortic Valve Replacement (TAVR) procedure
What this could lead to
If successful, this study could help doctors better understand whether TAVR is safe for patients with an enlarged aorta, potentially expanding treatment options for this group.
What could go wrong
This is a small, single-center study with only 101 participants, so results may not apply to all patients. It is observational, so it cannot prove cause and effect.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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the Affiliated Zhongshan Hospital of Dalian University
Dalian, Liaoning, 116001, China