SEVERE AORTIC STENOSIS
Clinical trials for SEVERE AORTIC STENOSIS explained in plain language.
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Could a common blood pressure pill protect the heart after valve replacement?
Disease control Not yet recruitingThis trial tests whether angiotensin receptor blockers (ARBs), a type of blood pressure medication, can reduce the risk of death or heart failure in people who have had a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis and still have a thickened heart mus…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: PHASE4 • Sponsor: Seoul National University Hospital • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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A new heart valve without Open-Heart surgery: can it help High-Risk patients?
Disease control Not yet recruitingThis trial is testing a new device called the Crea Aortic Valve, a replacement heart valve that can be implanted through a catheter without open-heart surgery. It is designed for people aged 60 and older with severe aortic stenosis—a narrowing of the heart's main valve—who are co…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Onecrea Medical Inc. • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New study aims to simplify care for patients with multiple leaky heart valves
Disease control Not yet recruitingThis study tests a step-by-step treatment plan for people with a narrowed aortic valve who also have leaky mitral or tricuspid valves. After a minimally invasive procedure to fix the aortic valve, doctors will check if the other valves still leak badly. If so, additional procedur…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Josep Rodes-Cabau • Aim: Disease control
Last updated Jun 27, 2026 13:01 UTC
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Can TAVI be done safely without a surgery team on standby?
Disease control Not yet recruitingThis study looks at whether a common heart valve procedure called TAVI is safe when done in hospitals that don't have heart surgery available on-site. About 600 people with severe aortic stenosis will be randomly assigned to have TAVI either with or without surgical backup. The g…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: PHASE4 • Sponsor: University of Alberta • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Robot helper for heart valve surgery? new device tested in 158 patients
Disease control Not yet recruitingThis study tests a new device called the TAVR Assist System, which helps doctors perform a heart valve replacement procedure (TAVR) for severe aortic stenosis. The trial will compare the assist system to the standard manual TAVR in 158 older adults. The goal is to see if the devi…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Zhicheng Medical Technology (Jiaxing) Co, Ltd • Aim: Disease control
Last updated Jun 27, 2026 09:02 UTC
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Heart drugs tested to stop AFib after TAVR
Prevention Not yet recruitingThis trial tests whether two heart medications, metoprolol and amiodarone, can prevent new-onset atrial fibrillation (AFib) in people who develop minor rhythm issues after transcatheter aortic valve replacement (TAVR). About 198 participants will be randomly assigned to one of th…
Matched conditions: SEVERE AORTIC STENOSIS
Phase: NA • Sponsor: Shanghai East Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:07 UTC
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Heart valve unit may cut brain fog after procedure, study hopes
Knowledge-focused Not yet recruitingThis study will follow 500 people with severe aortic stenosis who need a heart valve replacement. Researchers want to see if a dedicated Heart Valve Unit—a team of heart specialists working together—can reduce confusion, delirium, and memory problems that sometimes happen after t…
Matched conditions: SEVERE AORTIC STENOSIS
Sponsor: Heart and Brain Research Group, Germany • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC