SCHIZOPHRENIA

This study aimed to help people with early schizophrenia by combining long-acting injectable antipsychotic medication with cognitive and functional skills training. Researchers wanted to see if this approach could lead to symptom remission and better daily functioning. The study …

This study looked at the long-term safety of a medicine called iclepertin in adults with schizophrenia who had already completed earlier studies. Over 1,300 participants took iclepertin once a day for a year, along with their regular schizophrenia medication. The study was stoppe…

This study tested a 6-month dental health education program for people with schizophrenia to see if it improves oral hygiene and quality of life. Participants were randomly assigned to either the program or standard monitoring, and followed for 12 months. The study was terminated…

This study tested the drug cariprazine (Vraylar) for adults with schizophrenia in Japan and Taiwan. About 250 people were planned, but only 34 enrolled before the study was stopped early. Participants took either cariprazine or a placebo for 6 weeks, then could continue on caripr…

This study looked at whether oxytocin, a natural brain chemical that helps with social bonding, could improve social skills in veterans with schizophrenia. About 26 veterans took part. Researchers used brain scans to see how oxytocin affected brain activity and to find out who mi…

This study tested whether a drug called sodium nitroprusside (normally used for blood pressure) could reduce schizophrenia symptoms in people with early-stage illness. Researchers used a special eye scan to see if changes in tiny blood vessels in the retina could predict who woul…

This study looked at how well a digital tool called Horyzons works in clinics for people with early psychosis. Researchers talked to doctors and patients to find out what made it easy or hard to use. The goal was to learn how to better bring such tools into regular care.

This study looked at heart disease risk in 48 adults with schizophrenia, schizoaffective disorder, or bipolar disorder who were taking antipsychotic medications. Researchers measured blood fat ratios and heart electrical activity to understand how these drugs affect cardiovascula…

This study tested whether deep brain stimulation (dTMS) could help people with schizophrenia smoke less. Researchers used brain scans to see how the treatment changed brain connections and smoking habits. The study was small and ended early, so results are limited.

This study tested a smartphone-based program to help veterans with serious mental illness (like PTSD, bipolar disorder, or schizophrenia) who struggle to recognize their own emotions—a condition called alexithymia. The goal was to see if improving emotion awareness could lower su…