Brain zaps and computer games: a new hope for schizophrenia fog?

NCT ID NCT03741751

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested whether combining repetitive transcranial magnetic stimulation (rTMS) with computerized cognitive training could help adults with schizophrenia who have thinking and memory problems. Twelve participants received either active or sham rTMS followed by cognitive training for two weeks. The study was terminated early, so the findings are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
repetitive transcranial magnetic stimulation (rTMS) and computerized cognitive training
What this could lead to
If it works, this could point toward a way to improve thinking and memory in people with schizophrenia.
What could go wrong
This was a very small pilot study that was terminated early, so results are limited. It is not known if the combination is better than cognitive training alone.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction psychotic disorder Psychotic Disorders schizoaffective disorder schizophrenia Schizophrenia Spectrum and Other Psychotic Disorders

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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