SARCOMA

This early-stage trial tested whether a personalized immune cell therapy is safe for young adults with advanced soft tissue sarcoma. Doctors collected each patient's own tumor-fighting immune cells, grew them in a lab, and then infused them back after a brief chemotherapy treatme…

This study tested whether combining an immunotherapy drug (MK3475) with a low-dose chemotherapy (cyclophosphamide) could help control advanced sarcomas, a group of rare cancers. It involved 129 adults whose cancer had progressed despite prior treatments. The main goal was to see …

This study aimed to find a safe dose for a new two-drug combination (pembrolizumab and gemcitabine) for patients with advanced leiomyosarcoma or undifferentiated pleomorphic sarcoma, two aggressive types of soft tissue cancer. It involved 25 patients and focused primarily on iden…

This early-stage study tested a new immune therapy for children and young adults whose solid tumors did not respond to standard treatments. Doctors collected and grew a patient's own 'natural killer' (NK) immune cells, then gave them back to the patient to fight the cancer. The m…

This study tested a smartphone app called WeCanManage, designed to help cancer survivors manage long-term disabilities and symptoms after treatment. Twenty survivors of breast, head/neck, or sarcoma cancers tried the app to see if it was easy to use and helpful. The main goal was…

This study tested a mobile app program designed to help young adult cancer survivors manage their health after treatment. It aimed to reduce cancer-related distress and improve how well survivors follow recommended health check-ups. Researchers compared the app to standard online…

This study aims to understand when inflammation peaks in the body after starting a common type of cancer immunotherapy. Researchers measured markers in the blood of 98 adults with various cancers to see if these markers could predict side effects or interactions with other medica…

This study aimed to understand why older people are more likely to get certain cancers. Researchers collected small samples of healthy skin from 58 people in two age groups (18-40 and 55+) who were having surgery for a different condition. They analyzed these samples in a lab to …

This study used computer programs to analyze old medical records from 700 patients with two rare and aggressive bone cancers, osteosarcoma and Ewing's sarcoma. The goal was to find patterns in the data that could help predict which patients might have better or worse survival out…

This study looked back at the medical records of over 2,000 adults with advanced soft tissue sarcoma to understand what treatments they received in real-world clinics and how long they lived. Researchers analyzed patterns of care, including chemotherapy and off-label drug use, to…