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New hope for sarcoma patients: drug slows tumor growth in late-stage trial

NCT ID NCT01900743

Completed Disease control Sponsor: Centre Oscar Lambret Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug regorafenib in 219 adults with soft tissue sarcoma that had spread and was no longer responding to standard chemotherapy. Participants were randomly assigned to receive either regorafenib or a placebo. The main goal was to see if the drug could delay cancer growth or improve survival. The trial was completed and results help doctors understand if this treatment offers a meaningful benefit for this difficult-to-treat cancer.

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Conditions

The condition(s) this trial relates to.

Neoplasm Metastasis sarcoma soft tissue sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SARCOMA

Contacts and locations

Locations

  • AKH-Wien

    Vienna, 1090, Austria

  • Centre Alexis Vautrin

    Vandœuvre-lès-Nancy, 54519, France

  • Centre Antoine Lacassagne

    Nice, 06189, France

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre François Baclesse

    Caen, 14076, France

  • Centre GF Leclercq

    Dijon, 21079, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Léon Bérard

    Lyon, 69373, France

  • Centre Oscar Lambret

    Lille, 59020, France

  • Centre René Gauducheau

    Nantes, 44805, France

  • Hôpital Cochin

    Paris, 75014, France

  • Hôpital Saint Louis

    Paris, 75010, France

  • Hôpital St Jacques

    Besançon, 25000, France

  • Hôpital de La Timone

    Marseille, 13354, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Claudius Regaud

    Toulouse, 32052, France

  • Institut Curie

    Paris, 75005, France

  • Institut Curie - Hôpital René Huguenin

    Saint-Cloud, 92210, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Institut de Cancérologie Lucien Neuwirth (ICL)

    Saint-Priest-en-Jarez, 42270, France

  • Krankenhaus der Barmherzigen Schwestern Linz

    Linz, 4010, Austria

  • LKH

    Klagenfurt, Austria

  • Medizinische Universität Graz

    Graz, 8036, Austria

  • Universitätsklinik für Innere Medizin I

    Innsbruck, 6020, Austria

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