SARCOMA

This study looks at whether it's safe to leave the needle biopsy tract in place during surgery for extremity sarcoma. Currently, surgeons often remove the tract to prevent cancer cells from spreading, but this may not be necessary. The trial will compare cancer recurrence rates i…

This early-phase trial tests a radioactive drug called 177Lu-INN805 in 10 people with advanced solid tumors (head & neck, thyroid, lung, breast, or sarcoma) who have not responded to standard treatments. The main goals are to find a safe dose and check for side effects. Researche…

This early-phase study tests a new type of cell therapy for people with certain cancers (lymphoma, myeloma, and solid tumors like kidney cancer and sarcoma) that have returned or not responded to standard treatments. The therapy uses the patient's own T cells, which are modified …

This early-phase trial tests a new drug called BOLD-100 combined with standard chemotherapy (doxorubicin) in people with advanced soft tissue sarcomas that cannot be removed by surgery. The main goals are to find the safest dose and see how well the combination controls tumor gro…

This study tests a combination of three drugs (selumetinib, ZEN-3694, and durvalumab) in people with advanced sarcomas, including a rare nerve tumor called MPNST. The goal is to see if the combination is safe and can shrink tumors or stop them from growing. About 41 adults with s…

This study tests whether a special type of MRI (called pseudo-scanner) can map bone tumors as accurately as CT scans for surgical planning. About 122 people with bone sarcoma who need surgery will take part. If successful, this approach could reduce patients' exposure to radiatio…

This study looks at whether adding acupuncture to standard care can lower the chance of hospitalization from a serious side effect of chemotherapy called febrile neutropenia. 60 adults with sarcoma receiving a common chemo drug will be randomly assigned to get acupuncture during …

This study is testing a new AI chatbot designed to answer questions from people with sarcoma, a type of cancer. About 78 patients will use the chatbot for one month to see if it helps them feel less anxious and more satisfied with the information they get. The goal is to see if t…

This study is for young adults (ages 21-45) who had certain cancers as teens or young adults. Researchers are adapting a program that helps survivors manage their health and find the right follow-up care. The goal is to see if this program improves how confident and capable survi…

This study looks at whether it's possible to add three extra MRI scans during standard radiation treatment for soft tissue sarcoma. Only 5 adults will take part. The goal is simply to see if patients can complete these extra scans, not to test a new treatment.

This study is testing a mobile app called my.naviGATE for teens and young adults (ages 15-24) who have finished cancer treatment. The app provides personalized education, peer support, and tracks how patients are doing. Researchers want to see if using the app helps patients feel…

This study looks at how immunotherapy drugs (immune checkpoint inhibitors) might change the way the liver processes other medications. Researchers will give 80 cancer patients a mix of 7 common drugs to measure these effects. The goal is to understand and reduce side effects from…