PULMONARY TUBERCULOSIS
Clinical trials for PULMONARY TUBERCULOSIS explained in plain language.
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Could a common diabetes drug help fight TB in HIV patients?
Disease control CompletedThis study looked at whether adding metformin, a diabetes medicine, to standard antibiotics for tuberculosis (TB) is safe and tolerable for people also living with HIV. 112 adults with both HIV and TB took either standard TB drugs alone or with metformin for 11 weeks. Researchers…
Matched conditions: PULMONARY TUBERCULOSIS
Phase: PHASE2 • Sponsor: University of Massachusetts, Worcester • Aim: Disease control
Last updated May 17, 2026 08:49 UTC
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Breakthrough TB combo cures drug-resistant cases in major trial
Disease control CompletedThis study tested a 6-month treatment with three drugs (bedaquiline, PA-824, and linezolid) in 109 people with highly drug-resistant TB or TB that didn't respond to standard treatment. The goal was to see if the combination could cure the infection. Results showed high success ra…
Matched conditions: PULMONARY TUBERCULOSIS
Phase: PHASE3 • Sponsor: Global Alliance for TB Drug Development • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New TB cocktail shows promise in early trial
Disease control CompletedThis study tested a new drug called delpazolid, given with three standard TB medicines, to see if it is safe and works better than the standard drugs alone. 76 adults with newly diagnosed, drug-sensitive tuberculosis took part. The goal was to find the best dose and understand ho…
Matched conditions: PULMONARY TUBERCULOSIS
Phase: PHASE2 • Sponsor: LigaChem Biosciences, Inc. • Aim: Disease control
Last updated May 11, 2026 20:49 UTC
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New TB triage tests could speed up diagnosis and save lives
Diagnosis CompletedThis study tested two quick triage tests—CAD4TB software that analyzes chest X-rays and a C-reactive protein blood test—to see how accurately they can rule out pulmonary tuberculosis in adults with symptoms like cough or fever. Researchers enrolled 1,400 participants in Lesotho a…
Matched conditions: PULMONARY TUBERCULOSIS
Sponsor: Klaus Reither • Aim: Diagnosis
Last updated May 17, 2026 08:51 UTC