Breakthrough TB combo cures drug-resistant cases in major trial
NCT ID NCT02333799
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 23 times
Summary
This study tested a 6-month treatment with three drugs (bedaquiline, PA-824, and linezolid) in 109 people with highly drug-resistant TB or TB that didn't respond to standard treatment. The goal was to see if the combination could cure the infection. Results showed high success rates, offering a shorter, more effective option for a disease that is usually very difficult to treat.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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King DinuZulu Hospital Complex
Sydenham, Durban, 4001, South Africa
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Sizwe Tropical Disease Hospital
Sandringham, Johannesburg, 2131, South Africa
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Task Applied Science - Brooklyn Chest Hospital
Ysterplaat, Cape Town, 7405, South Africa
Conditions
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