PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

This study tested whether an investigational drug called 611 could help control moderate-to-severe chronic obstructive pulmonary disease (COPD) in Chinese adults. 142 participants who were already on standard COPD medications received either 611 or a placebo for 16 weeks. Researc…

This study tested an experimental drug called vapendavir to see if it could reduce serious lung symptoms in people with COPD after they caught a common cold virus. Researchers gave the drug or a placebo to 52 adults with moderate COPD who were then exposed to the virus. The main …

This study tested whether infusions of a type of adult stem cell (called PROCHYMAL) could safely help people with moderate to severe COPD. It involved 62 participants who were randomly assigned to receive either the stem cell treatment or a placebo. The main goals were to check f…

This study looked at how well a 3-in-1 inhaler called Trelegy works for people with symptomatic COPD in their daily lives. Over 460 adults with COPD used the inhaler for 12 weeks. Researchers measured changes in their breathing, shortness of breath, and overall health status to s…

This small, completed pilot study compared two ways to give oxygen to people hospitalized with a sudden worsening of their chronic lung disease (COPD). It tested a newer method called High-Flow Nasal Oxygen against the standard treatment, Noninvasive Ventilation, over the first 2…

This small pilot study tested whether an 8-week home program combining physical exercise with online brain training games is feasible and helpful for people with moderate to severe COPD. Researchers enrolled 24 participants to see if people could stick with the program and if doi…

This study tested whether using targeted nerve blocks with sedation is a safer and more effective way to control pain during leg amputation surgery compared to general anesthesia. It focused on high-risk patients with conditions like diabetes, heart disease, and lung disease. The…

This study tested whether a combination inhaler (Glycopyrrolate/Formoterol) could help people with COPD exercise for longer periods. 52 participants with moderate to severe COPD tried both the real medication and a placebo inhaler in a random order. The main goal was to see if th…

This study tested whether teaching specific breathing exercises through short videos could help people with COPD. 60 adults with COPD were split into two groups: one group learned and practiced the exercises daily for 30 days, while the other received standard care. Researchers m…

This study tested a new type of CT scan to see if it could better predict the risk of broken bones in people with Chronic Obstructive Pulmonary Disease (COPD). Researchers compared this new scan method to standard bone density tests in 560 current or former smokers, some with COP…

This study aimed to understand why many people with chronic obstructive pulmonary disease (COPD) experience severe muscle wasting, a condition linked to much higher mortality. Researchers compared muscle tissue samples from 22 COPD patients, some with muscle loss and some without…

This study aimed to understand how the body processes protein in people with chronic heart failure (CHF) or chronic obstructive pulmonary disease (COPD), conditions where dangerous weight and muscle loss often occur. Researchers compared 90 patients with these conditions to healt…

This study aimed to understand how breathing through a resistance, similar to an N95 mask, affects exercise and feelings of breathlessness in people with chronic lung disease (COPD). 52 former rehab patients walked on a treadmill with and without the breathing resistance. Researc…

This study tested whether data from a wearable sensor patch could help monitor chronic obstructive pulmonary disease (COPD) and predict symptom flare-ups. For three months, 77 people with COPD wore a patch that tracked things like activity, heart rate, breathing, and coughs. Rese…

This study aimed to better understand how the heart and lungs of people with chronic obstructive pulmonary disease (COPD) work during a specific 30-minute exercise test. Researchers observed 10 patients with moderate COPD while they performed an exercise routine with intense burs…

This study aimed to better understand Chronic Obstructive Pulmonary Disease (COPD) by closely tracking patients over 12 weeks. Researchers observed how daily symptoms, lung function, and markers of inflammation in the body changed and related to each other. The information gather…

This study tested whether a smartphone app could collect useful daily health information from people with COPD and other chronic conditions. Researchers followed 216 patients for up to 38 months to see if data from the app could help predict when their symptoms might get worse or…