PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

This study looked at how well the Trelegy Ellipta inhaler works for people with chronic obstructive pulmonary disease (COPD) in real-world settings. Over 12 weeks, 463 adults with COPD used the inhaler, which combines three medicines to help breathing. Researchers measured change…

This study tested an experimental drug called vapendavir in 52 adults with COPD (a chronic lung disease). The goal was to see if the drug could reduce severe cold symptoms caused by rhinovirus, a common cold virus. Participants were given either vapendavir or a placebo and monito…

This study tested a new drug, 611, in 142 Chinese adults with moderate to severe COPD. The goal was to see if it improves lung function and reduces symptoms compared to a placebo over 16 weeks. Participants were aged 40 to 85 and had a history of smoking.

This study tested whether a single intravenous infusion of PROCHYMAL stem cells is safe and can help people with moderate to severe COPD. 62 participants received either stem cells or a placebo and were followed for two years. The main goals were to check for side effects and mea…

This study tested a new scoring tool (GLORI-COPD) to see how well it can identify COPD patients who are at risk of serious complications, like lung infections. Researchers studied 462 smokers or former smokers aged 35 and older who had not been previously diagnosed with COPD. The…

This study looked at whether a simple blood test for circulating tumor cells (CTCs) can help detect lung cancer earlier in people at very high risk—smokers and ex-smokers over 55 with COPD. Researchers combined the blood test with low-dose CT scans over three yearly screenings. T…

This study tested whether an 8-week home program combining physical exercise with brain-training games is feasible for people with COPD. 24 participants aged 50+ tried the program, which aimed to improve both physical and mental function. The main goal was to see if people could …

This study tested whether a combination inhaler (Glycopyrrolate/Formoterol) helps people with COPD exercise longer compared to a placebo. 52 participants with stable COPD completed the trial. The main goal was to measure changes in exercise time on a stationary bike.

This study tested whether using nerve blocks with sedation instead of general anesthesia and opioids is safer and provides better pain control for high-risk patients needing an upper leg amputation. The study included 30 adults with conditions like diabetes, heart disease, or lun…

This study compared high-flow nasal oxygen (HFNO) to standard noninvasive ventilation in 51 people with moderate COPD flare-ups. The goal was to see if HFNO could improve blood oxygen and acid levels over 24 hours. Researchers also tracked safety and whether patients needed a bre…

This study tested whether teaching COPD patients simple breathing exercises through short videos could help them feel less short of breath, be more active, and sleep better. Sixty adults with COPD followed a 30-day program of pursed-lip and diaphragmatic breathing exercises using…

This study looked at how people with chronic heart failure or COPD process protein from meals. Researchers measured muscle building, body composition, and gut function in 90 adults aged 45 and older. The goal was to understand why weight and muscle loss happen, so better nutritio…

This study looked at how breathing through a facemask-like resistance affects exercise in people with chronic lung disease. 52 volunteers walked on a treadmill with and without extra inspiratory resistance. Researchers measured how hard they felt they were breathing and how well …

This study tested a wearable smart textile sensor system that can monitor heart signals, breathing, heart sounds, and movement. 334 healthy adults and people with high blood pressure or on dialysis wore the sensor alongside standard medical devices to see how well it worked. The …

This study looked at 560 current or former smokers with and without COPD to see if a new CT-based method can better measure bone health and predict fracture risk. The goal was to create a tool that uses CT scans of the spine, hip, and ankle to assess bone structure, not just dens…

This study followed 31 adults with COPD for 12 weeks to track how their symptoms, lung function, and markers of inflammation change over time. Researchers measured things like breathing tests, daily symptoms, and blood or sputum markers. The goal was to better understand COPD and…

This study followed 216 people with COPD and other health conditions for up to 38 months. Participants used a mobile app to log daily symptoms and other health data. The goal was to find patterns that could predict when a person's condition might get worse, helping doctors interv…

This study looked at how the heart and lungs of 10 people with moderate COPD respond during a 30-minute exercise test with short, intense work periods. Researchers found that lung artery pressure dropped after the first 5 minutes and heart output stayed steady, even with high-int…

This study looked at whether a wearable sensor (like a smartwatch) can help track symptoms and predict sudden worsening of COPD. 77 people with COPD wore the device for 3 months, while a small group without COPD wore it for 2 weeks. The goal was to see if data like heart rate, ac…

This study looked at whether special blood cells called fibrocytes are involved in muscle loss (sarcopenia) in people with COPD. Researchers compared muscle biopsies from 22 COPD patients with and without sarcopenia. The goal was to understand why muscle wasting happens, which co…