Could stem cells help breathe easier? new trial tests PROCHYMAL for COPD
NCT ID NCT00683722
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested whether infusions of PROCHYMAL, a stem cell product, are safe and can help people with moderate to severe COPD. 62 participants received either stem cells or a placebo. The main goal was to check for side effects, and researchers also looked at changes in lung function over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- PROCHYMAL (adult stem cells from bone marrow)
- What this could lead to
- If it works, this could point toward a new way to treat COPD by reducing inflammation and possibly improving lung function.
- What could go wrong
- This is an early phase 2 trial with only 62 people, so results may not apply to everyone. Stem cell treatments can have unknown long-term risks, and the placebo group may show similar benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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American Health Research
Charlotte, North Carolina, 28207, United States
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David Geffen School of Medicine at UCLA
Los Angeles, California, 90095, United States
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Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center
Torrance, California, 90502, United States
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Spartanburg Medical Research
Spartanburg, South Carolina, 29303, United States
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Upstate Pharmaceutical Research
Greenville, South Carolina, 29615, United States
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Vermont Lung Center, University of Vermont
Burlington, Vermont, 05446, United States
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