Could stem cells help breathe easier? new trial tests PROCHYMAL for COPD
NCT ID NCT00683722
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tested whether infusions of PROCHYMAL, a stem cell product, are safe and can help people with moderate to severe COPD. 62 participants received either stem cells or a placebo. The main goal was to check for side effects, and researchers also looked at changes in lung function over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PROCHYMAL (adult stem cells from bone marrow)
What this could lead to
If it works, this could point toward a new way to treat COPD by reducing inflammation and possibly improving lung function.
What could go wrong
This is an early phase 2 trial with only 62 people, so results may not apply to everyone. Stem cell treatments can have unknown long-term risks, and the placebo group may show similar benefits.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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American Health Research
Charlotte, North Carolina, 28207, United States
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David Geffen School of Medicine at UCLA
Los Angeles, California, 90095, United States
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Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center
Torrance, California, 90502, United States
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Spartanburg Medical Research
Spartanburg, South Carolina, 29303, United States
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Upstate Pharmaceutical Research
Greenville, South Carolina, 29615, United States
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Vermont Lung Center, University of Vermont
Burlington, Vermont, 05446, United States