PSORIASIS

This study is testing a new topical cream containing apremilast nanoparticles for people with mild to moderate plaque psoriasis. It will compare the new cream against a standard steroid cream and a combination of both. The goal is to see if the new cream can effectively treat pso…

This study aims to see if losing weight helps standard psoriasis treatments work better for overweight or obese adults. Researchers will compare two groups: one receiving standard psoriasis care plus a personalized weight loss plan (including diet, exercise, and possibly medicati…

This study aims to see how well and how safely the drug apremilast works for adults with moderate-to-severe psoriasis over 32 weeks. About 425 participants will take the drug and have their skin symptoms and quality of life checked at regular visits. The goal is to gather more re…

This study is testing a new flexible scheduling system for people with chronic skin conditions like eczema, psoriasis, or hives. Instead of fixed clinic appointments, patients use a smartphone app to report their symptoms monthly. The system then recommends if a clinic visit is n…

This study is testing whether a new oral medication called HSK44459 can safely reduce the skin symptoms of moderate to severe plaque psoriasis. About 150 adults will take either the drug or a placebo pill for 16 weeks to see how much their skin improves. The main goal is to see i…

This study is testing whether weekly video check-ins from an artificial intelligence (AI) doctor can help people with psoriasis use their prescribed cream more consistently. It will compare the AI check-ins to weekly video calls from a real person and to standard doctor visits. T…

This study is testing a new oral medication called RAP-103 to see if it can reduce the severity of psoriasis and improve patients' quality of life. It will involve about 90 adults with moderate-to-severe plaque psoriasis, who will take either the drug at one of two doses or a pla…

This study aims to develop a new, non-invasive way to help diagnose inflammatory skin diseases like psoriasis and eczema. Researchers will take high-resolution photos of the eyes of about 950 people, including patients and healthy volunteers, to look for patterns. They will use c…

This study compares two existing medications—methotrexate and apremilast—to see which works better at reducing the severe itching that often accompanies psoriasis. Eighty adults with psoriasis and bothersome itching will take one of the two drugs for eight weeks. Researchers will…

This study is testing a tiny device, about the size of a grain of rice, that is placed on the skin. The device contains tiny amounts of approved medications for eczema (atopic dermatitis) and psoriasis. Researchers aim to see if the device's local skin reaction can safely and eff…

This study aims to understand why people with psoriasis might have a higher risk of gum disease. Researchers will collect saliva and fluid from the gums of 60 participants with psoriasis to measure specific stress and immune system markers. The goal is to learn more about the bio…

This early-stage study aims to see how a new version of a psoriasis drug, called CMAB015, compares to an already approved drug, Cosentyx. It will involve 114 healthy Chinese men who will receive a single injection. Researchers will track how the drugs move through the body, check…

This study is creating a national registry to track the real-world results of two specific psoriasis drugs (guselkumab and risankizumab) in Costa Rica. It will follow 50 patients already receiving these medications as part of their normal care to see how well they control skin an…

This study will analyze existing medical records from 20,000 Italian patients with psoriasis, eczema, vitiligo, alopecia areata, or hidradenitis suppurativa. Researchers aim to understand how these conditions are treated in real-world practice and how patients' health evolves ove…

This study aims to understand if certain powerful psoriasis drugs affect a person's chance of developing or having recurring genital warts. It will follow 600 adults with moderate-to-severe psoriasis for two years, comparing those on different treatments. The research also explor…