PROSTATE CANCER METASTATIC
Clinical trials for PROSTATE CANCER METASTATIC explained in plain language.
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New hope for men with hard-to-treat prostate cancer?
Disease control Recruiting nowThis study tests a new drug called MK-5684 (opevesostat) against two standard drugs (abiraterone or enzalutamide) in men with a type of advanced prostate cancer that has spread and stopped responding to hormone therapy and chemotherapy. About 1,310 men will be randomly assigned t…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated May 15, 2026 11:58 UTC
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New hope for men with advanced prostate cancer: STAMPEDE2 trial tests targeted radiation and radioactive drug
Disease control Recruiting nowThis large phase 3 trial tests whether adding targeted radiotherapy (SABR) or a radioactive drug (PSMA-Lutetium) to standard hormone therapy helps men with metastatic prostate cancer live longer and slows cancer spread. About 3,360 participants from UK hospitals will be randomly …
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE3 • Sponsor: University College, London • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Immune cells from your own tumor could fight advanced cancer
Disease control Recruiting nowThis early-stage trial tests a new treatment made from a patient's own tumor-fighting immune cells (TILs) for metastatic colorectal or prostate cancer. The main goals are to see if it is safe and if repeated doses are possible. About 12 adults will receive the therapy and be moni…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE1, PHASE2 • Sponsor: Curacell Holding AB • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New hope for vulnerable prostate cancer patients: drug combo aims to delay disease worsening
Disease control Recruiting nowThis study tests whether adding darolutamide to standard hormone therapy (ADT) can slow cancer growth in men with metastatic prostate cancer who are not healthy enough for stronger treatments like chemotherapy. About 300 participants will receive either the drug combination or a …
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE3 • Sponsor: UNICANCER • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New radiation strategy aims to shrink prostate cancer further in men already on hormone therapy
Disease control Recruiting nowThis study tests whether adding precise, high-dose radiation to cancer spots seen on scans can help men with metastatic prostate cancer who are already responding to hormone therapy. About 80 men will be randomly assigned to get either standard care or standard care plus this tar…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE2 • Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New hope for advanced prostate cancer: enhertu trial launches
Disease control Recruiting nowThis study tests the drug Enhertu in 60 men with a specific type of advanced prostate cancer (HER2-positive) that has stopped responding to standard hormone therapy and chemotherapy. The goal is to see if Enhertu can shrink tumors or slow the cancer's growth. Participants must ha…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE2 • Sponsor: Washington D.C. Veterans Affairs Medical Center • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Exercise program aims to protect hearts of black prostate cancer patients
Disease control Recruiting nowThis study tests whether a 16-week exercise program designed for Black men can lower heart disease risk in those receiving hormone therapy for prostate cancer. Participants are randomly assigned to either the exercise group or usual care. The goal is to see if exercise improves h…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: NA • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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Exercise may fight prostate cancer cells, new study suggests
Disease control Recruiting nowThis study tests whether a 12-week exercise program can reduce the number of cancer cells in the blood of men with advanced prostate cancer. Twenty men on hormone therapy will participate. Researchers will measure changes in cancer cells and DNA before, during, and after the exer…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: NA • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated May 06, 2026 16:13 UTC
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Precision radiation may stall prostate cancer spread in early metastasis
Disease control Recruiting nowThis study tests whether adding targeted, high-dose radiation (SBRT) to cancer spots outside the prostate can delay the disease from getting worse in men with hormone-sensitive prostate cancer that has spread to just a few places. About 118 men will be randomly assigned to get ei…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: NA • Sponsor: Karin Soderkvist • Aim: Disease control
Last updated May 04, 2026 16:31 UTC
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New antibody targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis study tests a new antibody drug, OM-RCA-01, in people with advanced cancers that have a specific protein called FGFR1. The goal is to see if the drug is safe and can slow tumor growth. About 58 adults with kidney, lung, prostate, breast, or head & neck cancer will receive th…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE1, PHASE2 • Sponsor: Kidney Cancer Research Bureau • Aim: Disease control
Last updated May 04, 2026 16:24 UTC
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New imaging study aims to sharpen detection of advanced prostate cancer
Knowledge-focused Recruiting nowThis study tests whether a new way of analyzing PET scans (called dynamic imaging) can find more cancer spots in the body than the standard method. It involves 60 men with advanced prostate cancer that has spread and is no longer responding to hormone therapy. The goal is to impr…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: NA • Sponsor: Centre Henri Becquerel • Aim: Knowledge-focused
Last updated May 16, 2026 23:50 UTC
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Blood test may predict prostate cancer drug response
Knowledge-focused Recruiting nowThis study follows 120 men with advanced prostate cancer to see if markers in their blood can predict how well they respond to hormone therapy. Researchers will collect blood samples and compare markers from those who respond well to those who don't. The goal is to develop a test…
Matched conditions: PROSTATE CANCER METASTATIC
Sponsor: Duke University • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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New tool aims to make genetic testing clearer for black men with prostate cancer
Knowledge-focused Recruiting nowThis study is creating and testing a simple, patient-friendly tool to help Black or African American men with metastatic prostate cancer understand genetic testing for their tumors. Researchers want to see if the tool makes it easier for patients to learn about testing options an…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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Prostate cancer study investigates racial differences in drug response
Knowledge-focused Recruiting nowThis study follows men with metastatic prostate cancer who are receiving standard treatment with abiraterone and prednisone. Researchers want to see if a person's race or ethnicity affects how well the treatment works. The study will track PSA levels and genetic differences for u…
Matched conditions: PROSTATE CANCER METASTATIC
Phase: PHASE2 • Sponsor: Martha Mims • Aim: Knowledge-focused
Last updated May 15, 2026 11:56 UTC
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New study tests if PSMA PET scan can forecast prostate cancer treatment outcomes
Knowledge-focused Recruiting nowThis study looks at whether a type of scan called PSMA PET can help doctors predict how well advanced prostate cancer will respond to treatments like hormone therapy or chemotherapy. Researchers will track 1,300 men with advanced prostate cancer to see if scan results, such as th…
Matched conditions: PROSTATE CANCER METASTATIC
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated May 08, 2026 12:04 UTC
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Massive study launches to map prostate cancer across algeria
Knowledge-focused Recruiting nowThis study aims to understand the real-world picture of prostate cancer in Algeria. Researchers will observe 2,000 patients to learn about their backgrounds, how they were diagnosed, and what treatments they receive. The goal is to gather information to help improve future care, …
Matched conditions: PROSTATE CANCER METASTATIC
Sponsor: Société Algérienne de Formation et Recherche en Oncologie • Aim: Knowledge-focused
Last updated Apr 07, 2026 14:35 UTC