New hope for Hard-to-Treat prostate cancer: enhertu trial launches

NCT ID NCT06610825

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests Enhertu, a targeted drug, in 60 men with HER2-positive prostate cancer that has spread and stopped responding to hormone therapy and newer drugs like abiraterone. Participants must have tried or refused chemotherapy. The study measures tumor shrinkage and how long the cancer is controlled.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Enhertu (fam-trastuzumab deruxtecan-nxki)

What this could lead to

If it works, this could offer a new treatment option for men with HER2-positive prostate cancer that has stopped responding to hormone therapy and chemotherapy.

What could go wrong

This is a small, early-phase trial with only 60 people, so results may not apply to everyone. Enhertu can cause serious side effects like lung inflammation or heart problems.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Washington DC VAMC

    RECRUITING

    Washington D.C., District of Columbia, 20422, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact