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Could fasting help the immune system fight prostate cancer?

NCT ID NCT06826924

Recruiting now Knowledge-focused Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Source: ClinicalTrials.gov ↗

First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time

Summary

This study explores whether a 7-day water-only fast or ketone supplements are safe and doable for men with prostate cancer. The idea is that fasting may change the body's metabolism and boost immune cells to better attack cancer. Researchers will track side effects and how many participants complete the full 7 days, with the goal of designing future trials that combine fasting with cancer treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
water-only fasting or ketone supplementation
What this could lead to
If safe and feasible, this approach could pave the way for larger studies testing whether fasting or ketones help the immune system fight prostate cancer.
What could go wrong
This is a small, early feasibility study with only 40 participants, so results may not apply broadly. Fasting for 7 days carries risks like dehydration or nutrient deficiency.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Fasting metastatic prostate carcinoma prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER PROSTATE CANCER METASTATIC

Contacts and locations

Locations

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21231, United States

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