PROSTATE CANCER METASTATIC

This study tests an experimental drug called ARV-766, taken as a pill, for men with prostate cancer that has spread to other parts of the body. The drug is given alone or with another medication (abiraterone) to see if it is safe and can shrink tumors or lower PSA levels. About 1…

This study looks at whether adding focused radiation or surgery to all visible cancer sites, on top of usual hormone therapy, can delay cancer growth in men whose prostate cancer has spread to just a few places (up to 5 spots). About 409 men took part. The goal is to see if this …

This study tests a new drug called ST101 in people with advanced solid tumors that cannot be removed by surgery or have spread. The goal is to find a safe dose and see if the drug can shrink tumors. About 125 adults with cancers like glioblastoma, melanoma, breast, or prostate ca…

This study tests a new treatment called 177Lu-HTK03170 for men with a type of advanced prostate cancer that has stopped responding to hormone therapy. The treatment delivers radiation directly to cancer cells using a targeting molecule. The goal is to find a safe dose and see if …

This study tests a combination of two drugs, pembrolizumab and lenvatinib, in people with advanced neuroendocrine prostate cancer that has spread. The goal is to see if the treatment can slow tumor growth. About 45 participants will receive the drugs in 21-day cycles for up to 35…

This study looks at how two different prostate cancer medications, darolutamide and enzalutamide, affect thinking skills like memory and attention. About 111 men with advanced prostate cancer will take one of the two drugs and complete computer-based brain tests over time. The go…

This study tests whether a special type of PET scan, called PSMA PET, can track prostate cancer more accurately than usual scans like CT or bone scans. About 58 men with progressive or newly diagnosed prostate cancer will get PSMA PET scans over time. The goal is to see if change…