New radioactive drug takes aim at Hard-to-Treat prostate cancer

NCT ID NCT05570994

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a new radioactive drug, 177Lu-HTK03170, designed to seek out and destroy prostate cancer cells that have spread. It is for men with metastatic castration-resistant prostate cancer whose disease has worsened after other treatments. The trial will first find a safe dose, then measure how well it shrinks tumors and controls the cancer.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
177Lu-HTK03170 (a radioactive drug that targets prostate cancer cells)
What this could lead to
If successful, this could provide a new, personalized radiation treatment option for men with advanced prostate cancer that has stopped responding to standard therapies.
What could go wrong
This is an early-phase trial with only 50 participants, so the treatment may not prove effective or safe in larger groups. Potential side effects from radiation exposure are unknown at this stage.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • BC Cancer

    Vancouver, British Columbia, V5Z 4E6, Canada

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