New drug combo shows promise for rare, aggressive prostate cancer

NCT ID NCT04848337

First seen Feb 12, 2026 · Last updated May 05, 2026 · Updated 10 times

Summary

This study tests a combination of two drugs, pembrolizumab and lenvatinib, in people with advanced neuroendocrine prostate cancer that has spread. The goal is to see if the treatment can slow tumor growth. About 45 participants will receive the drugs in 21-day cycles for up to 35 cycles, as long as the cancer does not worsen and side effects are manageable.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Froedtert and The Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Oregon health

    Portland, Oregon, 97239, United States

  • University of Michigan Health System

    Ann Arbor, Michigan, 48109, United States

  • Winship Cancer Instituted of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.