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New hope for advanced prostate cancer: STAMPEDE2 trial tests targeted therapies

NCT ID NCT06320067

Recruiting now Disease control Sponsor: University College, London Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large Phase 3 trial tests whether adding targeted radiotherapy (SABR) or a radioactive drug (PSMA-Lutetium) to standard hormone therapy can slow cancer spread and improve survival in people with metastatic prostate cancer. About 3,360 participants across the UK will be randomly assigned to receive standard care alone or with one of the new treatments. The study monitors side effects and cancer progression over time.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PROSTATE CANCER METASTATIC

Contacts and locations

Locations

  • Addenbrookes

    RECRUITING

    Cambridge, United Kingdom

  • Barking, Havering and Redbridge University Hospitals NHS Trust

    RECRUITING

    Romford, United Kingdom

  • Barts Health NHS Trust

    RECRUITING

    London, United Kingdom

  • Churchill Hospital

    RECRUITING

    Oxford, United Kingdom

  • Derriford Hospital

    RECRUITING

    Plymouth, United Kingdom

  • Kings Mill Hospital

    RECRUITING

    Sutton in Ashfield, United Kingdom

  • Mount Vernon Hospital

    RECRUITING

    Barnsley, United Kingdom

  • North Middlesex Hospital

    RECRUITING

    London, United Kingdom

  • North Tees Health NHS Trust

    RECRUITING

    Stockton-on-Tees, United Kingdom

  • Queen Alexandra Hospital

    RECRUITING

    Portsmouth, United Kingdom

  • Royal Devon & Exeter Hospital

    RECRUITING

    Exeter, United Kingdom

  • Royal Devon University Hospital Trust

    RECRUITING

    Exeter, EX2 5DW, United Kingdom

  • Royal Free Hospital

    RECRUITING

    London, United Kingdom

  • The James Cook University Hospital

    RECRUITING

    Middlesbrough, United Kingdom

  • The Princess Alexandra Hospital

    RECRUITING

    Harlow, United Kingdom

  • The Royal Marsden Hospital

    RECRUITING

    London, SW3 6JJ, United Kingdom

  • The Royal Marsden Hospital

    RECRUITING

    Sutton, SM2 5PT, United Kingdom

  • University College London Hospitals NHS Foundation Trust

    RECRUITING

    London, NW3 2PG, United Kingdom

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