PRIMARY PERITONEAL CARCINOMA

This study tests a new drug called Rina-S in people with advanced solid tumors that have spread or can't be removed by surgery. The goal is to see if Rina-S is safe and how well it works against cancers like ovarian, lung, and breast cancer. About 764 participants will receive th…

This study tests if removing lymph nodes near the liver (hepato-celiac lymphadenectomy) can help control advanced or recurrent ovarian cancer. About 94 women with stage III/IV or platinum-sensitive recurrent ovarian cancer will have this surgery. The main goal is to see how many …

This study tests a new treatment using specially engineered immune cells (CAR-NK cells) that target two cancer markers at once. It is for people with ovarian, peritoneal, or fallopian tube cancer that has come back or not responded to at least two prior treatments. The therapy is…

This study is for women with advanced ovarian cancer that has been fully removed by surgery. It compares 3 cycles of chemotherapy followed by the maintenance drug niraparib against the standard 6 cycles plus niraparib. The goal is to see if the shorter chemo course works just as …

This phase 3 trial tests whether adding the experimental drug IMNN-001 to standard chemotherapy improves survival in people with advanced ovarian, fallopian tube, or primary peritoneal cancer. About 500 newly diagnosed participants will receive either the combination or chemother…

This early-phase study tests an experimental treatment called 27T51, a type of CAR T cell therapy that targets a protein (MUC16) found on certain cancer cells. It is for women with recurrent or hard-to-treat ovarian, peritoneal, or fallopian tube cancer. The study has two parts: …

This early-phase study tests a radioactive tracer called [18F]FTT to see if it can help PET/CT scans find more tumor cells in people with solid tumors, including ovarian, breast, and fallopian tube cancers. About 300 participants will receive the tracer and undergo imaging. The g…

This study compares giving cancer treatment at home versus in a clinic for 27 adults with various cancers in the Florida Panhandle. The goal is to see if patients prefer home care and if it is safe. Participants will receive their usual cancer drugs either at home or in the clini…

This study is gathering information and tumor samples from 2,000 people with low-grade ovarian or peritoneal tumors. The goal is to create a detailed database that helps researchers learn more about these rare cancers and how they are treated. This knowledge may lead to better tr…