New gene therapy combo aims to boost ovarian cancer survival

NCT ID NCT06915025

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests whether adding a gene therapy called IMNN-001 (given into the abdomen) to standard chemotherapy helps people with advanced ovarian, fallopian tube, or peritoneal cancer live longer. About 500 newly diagnosed patients will be randomly assigned to receive either chemo alone or chemo plus IMNN-001. The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IMNN-001 (a gene therapy given into the abdomen)

What this could lead to

If it works, this could offer a new treatment option that extends survival for people with advanced ovarian cancer.

What could go wrong

This is a large phase 3 trial, but the added therapy may not improve outcomes over chemo alone and could cause more side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Carcinoma, Ovarian Epithelial fallopian tube cancer fallopian tube neoplasm ovarian cancer ovarian carcinoma primary peritoneal carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advent Health

    RECRUITING

    Orlando, Florida, 32804, United States

    Contact Email: •••••@•••••

    Contact

  • Erlanger Health

    RECRUITING

    Chattanooga, Tennessee, 37403, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact

  • Froedtert and The Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Email: •••••@•••••

    Contact

  • Providence Cancer Institute

    RECRUITING

    Portland, Oregon, 97213, United States

    Contact

    Contact Email: •••••@•••••

  • Providence Sacred Heart Medical Center & Children's Hospital

    RECRUITING

    Spokane, Washington, 99204, United States

    Contact Email: •••••@•••••

    Contact

  • Sanford Health

    RECRUITING

    Sioux Falls, South Dakota, 57104, United States

    Contact Email: •••••@•••••

    Contact

  • Washington University School of Medicine in St. Louis

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact

    Contact Email: •••••@•••••